血府逐瘀汤治疗稳定型心绞痛的研究进展

Research Progress on the Treatment of Stable Angina Pectoris with Xuefu Zhuyu Decoction

摘要: 稳定型心绞痛(stable angina pectoris, SAP)作为心血管疾病中的常见类型，严重影响患者的生活质量与健康状况，探寻有效的治疗手段一直是医学研究的重要方向。血府逐瘀汤源于中医经典理论，近年来其在稳定型心绞痛治疗中的应用受到广泛关注。相关研究多采用随机对照试验、前瞻性研究等方法，通过对临床症状、心电图、心功能等多指标的观察，评估血府逐瘀汤的疗效。研究表明，血府逐瘀汤在缓解稳定型心绞痛症状、改善心电图表现、提高运动耐量等方面具有显著效果。其作用机制主要涉及调节血脂、抗血小板聚集等，在细胞、分子水平上也发挥着重要作用。本研究对于深入挖掘中医经典方剂的治疗潜力，优化稳定型心绞痛的治疗方案，提高患者生活质量具有重要意义，为稳定型心绞痛的临床治疗提供了新的思路与方法。

Abstract: Stable angina pectoris is a common and frequently occurring disease in cardiovascular diseases, which significantly affects patients’ quality of life, physical health and safety. In recent years, with the increasing attention to traditional Chinese medicine in the treatment of cardiovascular diseases, Xuefu Zhuyu Decoction, as a classic traditional Chinese medicine prescription, has shown potential value in the treatment of stable angina pectoris. The research methods mainly include clinical research and experimental research. In clinical research, relevant cases are collected and sorted out, and research methods such as randomized controlled trials are adopted to observe indicators such as symptom relief, electrocardiogram indicators and cardiac function indicators. Experimental research explores the action mechanism of Xuefu Zhuyu Decoction from the aspects of cardiovascular system and modern medical perspectives. The main efficacy of Xuefu Zhuyu Decoction in the treatment of stable angina pectoris includes relieving symptoms, improving electrocardiogram, enhancing exercise tolerance, regulating blood lipid levels, and antiplatelet aggregation. Its action mechanisms involve multiple aspects, such as adjusting blood lipid metabolism, inhibiting platelet aggregation, and acting at the cellular and molecular levels. This research has important significance and value. It not only provides a more comprehensive understanding of the application of Xuefu Zhuyu Decoction in the treatment of stable angina pectoris, but also provides a reference for optimizing treatment plans, exploring combined drug use and preventing recurrence, which is conducive to improving the overall treatment level of stable angina pectoris.