肌少症指数与2型糖尿病并发颈动脉粥样硬化的相关性分析
Analysis of the Correlation between Sarcopenia Index and Concurrent Carotid Atherosclerosis in Type 2 Diabetes Mellitus
DOI: 10.12677/acm.2025.15102742, PDF,    科研立项经费支持
作者: 胥方琴, 徐俊马*, 谢 翼, 邵 婵, 郦 超, 潘 良：常州市金坛第一人民医院老年医学科，江苏 常州
关键词: 糖尿病；颈动脉粥样硬化；肌少症指数；Diabetes Mellitus； Carotid Atherosclerosis； Sarcopenia Index
摘要: 目的：探讨肌少症指数与2型糖尿病(T2DM)并发动脉粥样硬化的相关性。方法：选取2023年1月至2024年8月入住常州市金坛第一人民医院老年医学科的T2DM患者120例，根据是否并发颈动脉粥样硬化将入选患者分为单纯糖尿病组60例、T2DM并发颈动脉粥样硬化组60例，采集临床信息、代谢指标，并计算肌少症指数(SI)。分析T2DM患者并发颈动脉粥样硬化的影响因素，评价肌少症指数与T2DM患者并发颈动脉粥样硬化的相关性。结果：病程、空腹血糖、糖化血红蛋白、总胆固醇、甘油三酯、SI是T2DM患者并发颈动脉粥样硬化的影响因素。ROC曲线分析提示，SI预测糖尿病并发颈动脉粥样硬化的AUC为0.703，灵敏度为0.966，特异度为0.339。结论：SI降低是T2DM患者并发颈动脉粥样硬化的危险因素，提示SI可作为预测T2DM患者并发颈动脉粥样硬化的评估工具。
Abstract: Objective: To investigate the correlation between the sarcopenia index (SI) and atherosclerosis in patients with type 2 diabetes mellitus (T2DM). Methods: 120 T2DM patients admitted to the Department of Geriatrics at Jintan First People’s Hospital of Changzhou from January 2023 to August 2024 were enrolled. Participants were divided into two groups: a diabetes-only group (60 cases) and a T2DM with carotid atherosclerosis group (60 cases). Clinical information, metabolic indicators, and SI were collected. Factors influencing carotid atherosclerosis in T2DM patients were analyzed, and the correlation between SI and carotid atherosclerosis was evaluated. Results: Duration of diabetes, fasting blood glucose, glycated hemoglobin (HbA1c), total cholesterol (TC), triglycerides (TG), and SI were identified as influencing factors for carotid atherosclerosis in T2DM patients. ROC curve analysis revealed that SI predicted carotid atherosclerosis with an AUC of 0.703, sensitivity of 0.966, and specificity of 0.339. Conclusion: Reduced SI is a risk factor for carotid atherosclerosis in T2DM patients, suggesting that SI may serve as an assessment tool for predicting carotid atherosclerosis in this population.
文章引用：胥方琴, 徐俊马, 谢翼, 邵婵, 郦超, 潘良. 肌少症指数与2型糖尿病并发颈动脉粥样硬化的相关性分析[J]. 临床医学进展, 2025, 15(10): 177-183. https://doi.org/10.12677/acm.2025.15102742

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