猫鼻腺癌并发急性失明的多模态诊断与治疗分析

Multimodal Diagnosis and Treatment Analysis of Acute Blindness Complicating Nasal Adenocarcinoma in a Cat

摘要: 猫鼻腺癌(Feline nasal adenocarcinoma, FNA)是一种罕见且具有高度侵袭性的恶性肿瘤，好发于中老年猫。该肿瘤侵袭性强，可累及视神经通路导致急性失明，预后谨慎至不良。目前国外相关病例报道罕见，本文系国内首次报道FNA并发急性失明的病例。2023年9月，我院接诊一例FNA并发急性失明的病例，经肿瘤减容手术及病理确诊后，短期症状改善，但最终因肿瘤转移实施安乐死。本文详细报告该病例的诊疗过程、影像学特征(重点展示肿瘤沿鼻腔–额窦–视神经侵袭路径)及转归，旨在为临床诊疗提供参考，并强调早期多模态影像学诊断及综合治疗的重要性。

Abstract: Feline nasal adenocarcinoma (FNA) is a rare malignant tumor predominantly affecting middle-aged and senior cats. Its aggressive nature can lead to invasion of the optic nerve pathways, resulting in acute blindness and a guarded to poor prognosis. While international reports of FNA-associated blindness are scarce, no such cases have been documented domestically in China. In September 2023, a cat presenting with acute blindness secondary to FNA was admitted to our hospital. Tumor debulking surgery was performed to alleviate optic nerve compression and obtain a definitive histopathological diagnosis. Short-term symptomatic improvement was achieved; however, the cat was ultimately euthanized due to tumor metastasis. This report details the clinical presentation, diagnostic imaging (notably MRI tracking the tumor’s path from nasal cavity/frontal sinus to optic nerves), therapeutic intervention, and outcome. It serves as a reference for clinicians and underscores the critical role of early advanced imaging and multimodal therapy.