天麻钩藤饮治疗儿童抽动障碍的研究进展

Research Progress on the Treatment of Tic Disorders in Children with Tianma Gouteng Decoction

摘要: 抽动障碍是儿童或青少年时期临床上常见的一种神经精神障碍性疾病，是影响儿童身心健康的主要因素。我国抽动障碍患儿逐年增加。其病因及发病机制复杂，目前西药治疗主要包括巴胺受体激动剂、多巴胺受体阻滞剂、选择性5-羟色胺再摄取抑制剂、选择性单胺能拮抗剂、中枢性α受体激动剂及抗癫痫药物等，长期服用此类药物存在一定的副作用，甚至还会出现戒断反应。中医药在治疗抽动障碍方面有着独特的优势，可以多成分、多靶点进行整体调节，天麻钩藤饮是我国传统的中药方剂，近年来对天麻钩藤饮的研究越来越深入，本文就天麻钩藤饮的研究进展进行综述，为以后的深入研究提供参考。

Abstract: Tic disorder is a common neuropsychiatric disorder in clinical practice during childhood or adolescence, and it is a major factor affecting children’s physical and mental health. The number of children with tic disorders in our country has been increasing year by year. The etiology and pathogenesis of this disease are complex. Currently, Western medicine treatment mainly includes dopamine receptor agonists, dopamine receptor blockers, selective serotonin reuptake inhibitors, selective monoaminergic antagonists, central alpha receptor agonists and antiepileptic drugs, etc. Long-term use of such drugs has certain side effects and may even lead to withdrawal reactions. Traditional Chinese medicine has unique advantages in the treatment of tic disorders, capable of conducting overall regulation with multiple components and targets. Tianma Gouteng Decoction is a traditional Chinese medicine formula in China. In recent years, research on Tianma Gouteng Decoction has become increasingly in-depth. This article reviews the research progress of Tianma Gouteng Decoction to provide a reference for future in-depth studies.