肝细胞癌患者术前红细胞分布宽度与白蛋白比值的临床意义

The Clinical Significance of Red Cell Distribution Width and Albumin Ratio before Operation in Patients with Hepatocellular Carcinoma

摘要: 目的：探讨肝细胞癌患者术前红细胞分布宽度(RDW)与白蛋白(Alb)比值在腹腔镜肝癌部分切除术后预后中的关系。方法：回顾性分析2016年1月至2023年7月间于青岛大学附属医院接受腹腔镜肝部分切除术的肝细胞癌患者资料，收集患者的临床资料、术前实验室检查结果以及术后随访数据。统计分析术前RDW/Alb比值与患者术后预后情况的关系。结果：共纳入544例肝细胞癌患者，其中术前RDW/Alb比值高的患者术后生存率显著低于比值正常的患者(P < 0.05)。术前RDW/Alb比值与术后并发症发生率呈显著相关(P < 0.01)。多因素分析显示，术前RDW/Alb比值是影响患者术后预后的独立危险因素。结论：肝细胞癌患者术前RDW/Alb比值可作为评估患者手术后预后的重要指标之一，高比值提示患者预后不佳，术前应加强干预措施，以提高手术成功率和患者生存质量。

Abstract: Objective: To investigate the relationship between preoperative red blood cell distribution width (RDW) and albumin (Alb) ratio in the prognosis of patients with hepatocellular carcinoma after laparoscopic partial resection. Method: A retrospective analysis was conducted on the data of hepatocellular carcinoma patients who underwent laparoscopic partial hepatectomy at Qingdao University Affiliated Hospital from January 2016 to July 2023. Clinical data, preoperative laboratory test results, and postoperative follow-up data were collected from the patients. Statistical analysis of the relationship between preoperative RDW/Alb ratio and postoperative prognosis of patients. Result: A total of 544 patients with hepatocellular carcinoma were included, among whom patients with high preoperative RDW/Alb ratios had significantly lower postoperative survival rates than those with normal ratios (P < 0.05). The preoperative RDW/Alb ratio was significantly correlated with the incidence of postoperative complications (P < 0.01). Multivariate analysis showed that the preoperative RDW/Alb ratio is an independent risk factor affecting the postoperative prognosis of patients. Conclusion: The preoperative RDW/Alb ratio in hepatocellular carcinoma patients can be used as one of the important indicators to evaluate the postoperative prognosis. A high ratio indicates poor prognosis, and preoperative intervention measures should be strengthened to improve the success rate of surgery and the quality of life of patients.