前沿科研成果融入天然药物化学实验教学——以积雪草苷的提取和测定为例
Integrating Cutting-Edge Research Findings into Experimental Teaching in Natural Product Chemistry—Taking the Extraction and Measurement of Asiaticoside as an Example
摘要: 掌握伞形科植物积雪草中积雪草苷的提取和含量测定是天然药物化学实验课程教学的重要部分。以天然植物积雪草为研究对象,对积雪草进行提取,将所提取的积雪草苷样品进行测定,确定目标化合物的含量。该实验教学通过天然植物活性成分的提取与定量分析,帮助学生掌握相关实验技术,培养其科研思维和实践能力。学生在实验过程中不仅能学习专业知识和操作技能,还能提升问题分析与解决能力。同时,该实验有助于增强学生对天然植物资源的认知,为其今后开展植物资源开发利用研究奠定基础。
Abstract: Mastering the extraction and concentration determination of asiaticoside from Centella asiatica, a plant belonging to the Apiaceae family, constitutes a vital component of the natural medicinal chemistry laboratory course. Using the natural plant Centella asiatica as the research subject, students perform extractions and subsequently determine the concentration of the extracted asiaticoside standard samples and asiaticoside samples. This experimental teaching approach helps students master relevant laboratory techniques and cultivate scientific thinking and practical skills through the extraction and quantitative analysis of natural plant active components. During the experiment, students not only acquire specialized knowledge and operational skills but also enhance their problem-solving abilities. Additionally, this experiment contributes to deepening students’ understanding of natural plant resources, laying a foundation for their future research in plant resource development and utilization.
参考文献
|
[1]
|
项佳媚, 肖伟, 许利嘉, 等. 积雪草的研究进展[J]. 中国现代中药, 2016, 18(2): 233-238+258.
|
|
[2]
|
秦慧真, 林思, 邓玲玉, 等. 积雪草苷的药理作用及机制研究进展[J]. 中国药房, 2021, 32(21): 2683-2688.
|
|
[3]
|
He, Z., Hu, Y., Niu, Z., Zhong, K., Liu, T., Yang, M., et al. (2023) A Review of Pharmacokinetic and Pharmacological Properties of Asiaticoside, a Major Active Constituent of Centella asiatica (L.) Urb. Journal of Ethnopharmacology, 302, Article ID: 115865. [Google Scholar] [CrossRef] [PubMed]
|
|
[4]
|
翟长远, 李敏通, 王转卫, 等. 师生身份互换式本科教学方法实践与分析[J]. 高等农业教育, 2014(1): 62-64.
|
|
[5]
|
臧轶楠. 关于高校师生关系的思考[J]. 北京教育(德育), 2013(3): 47-48.
|
|
[6]
|
张学博 刘依蒙, 杨明. 基于创新能力培养的高校实验教学体系构建[J]. 高教学刊, 2024, 10(3): 108-111.
|
|
[7]
|
王秋芬, 张会菊, 范云场, 等. 碎片化教学在化学综合实验中的应用与效果——以“SnS2材料的制备及储锂性能研究”为例[J]. 实验室研究与探索, 2022, 41(4): 206-210.
|