针刺治疗围绝经期失眠机制的研究进展
Research Progress on the Mechanism of Acupuncture Treatment for Perimenopausal Insomnia
DOI: 10.12677/tcm.2025.1410608, PDF,   
作者: 叶升虎, 李裕章, 张静怡, 吴 丹：广西中医药大学研究生院，广西 南宁；刘运珠*：广西中医药大学第一附属医院针灸科，广西 南宁
关键词: 针刺疗法；失眠；研究；综述；Acupuncture therapy； Insomnia； Research； Summary
摘要: 围绝经期失眠是困扰女性健康的常见问题，显著危害患者的身心健康。本文旨在梳理针刺干预该疾病潜在的作用机制。着重探讨其对核心生理系统的多靶点干预作用：包括神经内分泌轴(HPO轴、HPA轴)功能、神经递质平衡、性激素分泌稳态的调节；对机体氧化应激与炎症反应的抑制；以及对肠–脑互动机制、自主神经系统张力的调控。同时涵盖针刺调控脑功能生理活动的协同干预机制。本研究旨在为围绝经期失眠的针刺临床应用及机制深化研究奠定理论基础。
Abstract: Insomnia during the perimenopausal period is a common problem affecting women’s health, significantly harming their physical and mental well-being. This article aims to review the potential mechanisms of acupuncture intervention for this disease. It focuses on its multi-target intervention effects on the core physiological systems: including the functions of the neuroendocrine axis (HPO axis, HPA axis), neurotransmitter balance, regulation of sex hormone secretion homeostasis; inhibition of oxidative stress and inflammatory responses in the body; as well as regulation of the intestinal-brain interaction mechanism and tension of the autonomic nervous system. It also covers the synergistic intervention mechanism of acupuncture in regulating the physiological activities of the brain function. This study aims to lay a theoretical foundation for the clinical application of acupuncture for perimenopausal insomnia and the in-depth research on its mechanism.
文章引用：叶升虎, 李裕章, 张静怡, 吴丹, 刘运珠. 针刺治疗围绝经期失眠机制的研究进展[J]. 中医学, 2025, 14(10): 4189-4195. https://doi.org/10.12677/tcm.2025.1410608

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