21世纪以来国内外妊娠期高血压疾病文献计量分析

Bibliometric Analysis of Domestic and International Research on Hypertensive Disorders of Pregnancy Since the 21st Century

摘要: 目的：基于CiteSpace与地理空间分析方法探究21世纪以来国内外妊娠期高血压疾病的研究热点、发展趋势，以及研究资源与疾病负担间的空间匹配关系，为后续研究提供借鉴。方法：基于中国知网(CNKI)与Web of Science数据库，筛选2000年至2023年间发表的相关文献，运用CiteSpace6.4.R1进行计量分析，并结合地理空间分析方法，揭示其研究发文机构空间分布与主要疾病负担区域的匹配状况。结果：(1) 全球范围内，妊娠期高血压疾病研究发文量在2020年之前总体呈上升趋势。(2) 研究主要发文机构在空间上集聚于北美、欧洲和中国东部等经济发达地区，与非洲、中国西部等疾病高负担区域存在研究资源与实际健康需求的空间错位。(3) 在不同地理环境及社会经济文化背景影响下，国内外研究主题存在差异。国内研究更关注疾病的临床治疗和临床效果，而国际研究侧重于疾病对母婴造成的长期健康影响以及风险因素的全面探究。(4) 孕产妇的心理健康及多维度风险因素，探索新型干预与预防措施是当前国内外的研究重点。结论：当前全球妊娠期高血压疾病的研究存在研究资源–需求空间错位状况，未来应优先将研究资源和医疗保障向高负担地区和脆弱人群倾斜。同时，加强对疾病长期健康效应和有效干预措施的探索，更有效地应对疾病带来的挑战。

Abstract: Objective: To explore the research hotspots, development trends, and the spatial matching relationship between research resources and disease burden of hypertensive disorders of pregnancy (HDP) since the 21st century, based on CiteSpace and geospatial analysis, so as to provide references for future studies. Methods: Relevant publications from 2000 to 2023 were retrieved from the China National Knowledge Infrastructure (CNKI) and the Web of Science (WOS). CiteSpace 6.4.R1 was applied for bibliometric analysis, combined with geospatial methods to reveal the spatial distribution of research institutions and their alignment with regions bearing the major disease burden. Results: (1) Globally, the number of publications on HDP generally showed an upward trend before 2020. (2) Research institutions were spatially concentrated in economically developed regions such as North America, Europe, and eastern China, while a spatial mismatch was observed between these research resources and high-burden areas including Africa and western China. (3) Influenced by different geographical, socioeconomic, and cultural contexts, research themes varied across countries. Domestic studies placed greater emphasis on clinical treatment and therapeutic outcomes, whereas international studies focused more on the long-term health effects on mothers and infants, as well as comprehensive investigations of risk factors. (4) Current research hotspots at home and abroad include maternal mental health, multidimensional risk factors, and the exploration of novel interventions and preventive strategies. Conclusion: A spatial mismatch exists globally between research resources and the actual needs regarding HDP. Future efforts should prioritize the allocation of research resources and healthcare support to high-burden regions and vulnerable populations. Meanwhile, strengthening the exploration of long-term health effects and effective intervention measures will be essential to address the challenges posed by the disease.