乳腺经典型浸润性筛状癌1例临床病理分析

Clinicopathological Analysis of 1 Case of Breast Classic Invasive Cribriform Carcinoma

摘要: 目的：探讨乳腺经典型浸润性筛状癌患者的临床病理特征，增加对此类疾病的认识，减少漏诊误诊，为治疗提供依据。方法：报道1例经典型浸润性筛状癌的病理特征，回顾分析浸润性筛状癌病理特征及鉴别诊断的相关文献报道。结果：肿瘤细胞由不规则的巢团状或岛状结构组成，结构单一，细胞低–中核级，肌上皮消失，为低级别乳腺肿瘤，患者行乳腺癌改良根治术，规律服用内分泌药物，未发现转移和复发。结论：乳腺经典型浸润性筛状癌以低级别乳腺肿瘤病理学特点为主，无特殊临床特征，预后良好，通过报道提升对该疾病的认知，及诊疗水平，减轻患者心理压力，改善患者生存率。

Abstract: Objective: To investigate the clinicopathological features of patients with breast classic invasive cribriform carcinoma, enhance the understanding of such diseases, reduce missed diagnoses and misdiagnoses, and provide a basis for treatment. Methods: The pathological features of 1 case of classic invasive cribriform carcinoma were reported, and the relevant literature on the pathological features and differential diagnosis of invasive cribriform carcinoma was reviewed and analyzed. Results: The tumor cells were composed of irregular nest-like or island-like structures with a single structure. The cells were of low to intermediate nuclear grade, and myoepithelial cells were absent, indicating a low-grade breast tumor. The patient underwent modified radical mastectomy, took endocrine drugs regularly, and no metastasis or recurrence was found. Conclusion: Breast classic invasive cribriform carcinoma is mainly characterized by low-grade breast tumor pathology, with no special clinical features and a good prognosis. This report aims to improve the understanding of the disease, enhance the level of diagnosis and treatment, reduce patients’ psychological pressure, and improve patients’ survival rate.