颅脑损伤患者术后颅内感染的危险因素分析及预防措施
Risk Factors Analysis and Preventive Measures of Postoperative Intracranial Infection in Patients with Craniocerebral Injury
DOI: 10.12677/acm.2025.15103000, PDF,   
作者: 赵海宏, 黄 斌：重庆医科大学附属第二医院重症医学科，重庆
关键词: 颅内感染；颅脑手术；危险因素；颅脑损伤；Intracranial Infection； Brain Surgery； Risk Factors； Craniocerebral Injury
摘要: 颅内感染是颅脑损伤术后严重的并发症，致残率与死亡率高。本文系统综述颅脑损伤术后颅内感染的危险因素及阐明其病理生理机制，包括年龄、低GCS评分、低蛋白血症、高血糖、手术时间 ≥ 4小时、多次手术、后颅窝手术、开放性损伤、脑脊液漏及留置引流管等，并提出相应的防控策略。文中进一步讨论了现有研究的局限性、临床面临的挑战以及未来研究方向，旨在为临床早期识别高危患者及提高颅内感染患者的预后提供理论依据。
Abstract: Intracranial infection is a serious complication after craniocerebral injury, with high morbidity and mortality. This article systematically reviews the risk factors of intracranial infection after craniocerebral injury and elucidates its pathophysiological mechanism, including age, low GCS score, hypoproteinemia, hyperglycemia, operation time ≥ 4 hours, multiple operations, posterior fossa surgery, open injury, cerebrospinal fluid leakage and indwelling drainage tube, and proposes corresponding prevention and control strategies. This article further discusses the limitations of existing research, clinical challenges and future research directions, aiming to provide a theoretical basis for early identification of high-risk patients and improving the prognosis of patients with intracranial infection.
文章引用：赵海宏, 黄斌. 颅脑损伤患者术后颅内感染的危险因素分析及预防措施[J]. 临床医学进展, 2025, 15(10): 2190-2195. https://doi.org/10.12677/acm.2025.15103000

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