止血类中药治疗溃疡性结肠炎的研究进展

Research Progress on Hemostatic Chinese Herbal Medicines in the Treatment of Ulcerative Colitis

摘要: 溃疡性结肠炎(ulcerative colitis, UC)是一种慢性非特异性炎症性肠病(inflammatory bowel disease, IBD)，据近20余年流行病学调查我国UC就诊人数趋势快速上升，本病病因尚未明确发病机制复杂，且其临床转归多样、治疗效果难以预测。便血、脓血粘液便作为UC常见临床症状常成为患者首次就诊的主要原因。中医在UC的诊疗上已取得了可观效果，其优势在临床治疗及科学研究上逐渐被证实。本文通过检索中国知网、超星期刊、万方数据、古今医案云平台，收集中医治疗UC的方剂，统计治疗UC的常用止血类中药，并通过整合近年的相关研究成果，探讨常用中药药物治疗UC的作用机制，以期为中医临床用药治疗UC提供新参考。

Abstract: Ulcerative colitis (UC) is a chronic non-specific inflammatory bowel disease (IBD). Epidemiological surveys over the past two decades indicate a rapidly increasing trend in the number of UC patients in China. The etiology of UC remains unclear, its pathogenesis is complex, and its clinical outcomes are diverse, making therapeutic efficacy difficult to predict. Hematochezia and mucopurulent bloody stools, as common clinical symptoms of UC, often serve as the primary reasons for patients’ initial medical consultations. Traditional Chinese Medicine (TCM) has achieved remarkable results in the diagnosis and treatment of UC, with its advantages increasingly demonstrated in both clinical practice and scientific research. This paper retrieves data from CNKI, Chaoxing Periodicals, Wanfang Data, and the Ancient and Modern Medical Case Cloud Platform to collect TCM prescriptions for UC treatment, identifies commonly used hemostatic Chinese herbs for UC, and integrates recent relevant research findings to explore the mechanisms of action of these herbs. The aim is to provide new references for the clinical application of TCM in treating UC.