APD与CAPD在终末期肾脏病治疗中超滤量的比较
Comparison of Ultrafiltration Volume between APD and CAPD in Treatment of End-Stage Renal Disease
摘要: 慢性肾脏病的全球患病率已达13.4%，CKD早已成为影响全球的重大公共健康问题。目前持续不卧床腹膜透析(continuous ambulatory peritoneal dialysis, CAPD)和自动化腹膜透析(automated peritoneal dialysis, APD)是两种常用的腹膜透析治疗模式。我国APD起步较晚且发展不均衡，尤其在基层医院中，APD应用率相较于CAPD更低。基于此背景，本研究设计对照试验旨在探讨APD与CAPD治疗二者超滤量及住院时间差异。最终纳入了62例进行维持性腹膜透析的终末期肾脏病患者，将入组患者随机分为两组，一组使用APD治疗，另一组使用CAPD治疗。结果显示相较于CAPD治疗，APD显著增加了患者的超滤量，尤其在低腹膜溶质转运功能的患者中超滤量相较于使用CPAD治疗者更多，且住院病人能在更短的时间内达到治疗效果(结果具有统计学意义，P < 0.05)。
Abstract: The global prevalence of chronic kidney disease has reached 13.4%, and CKD has long been a major public health problem affecting the whole globe. At present, continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal dialysis (APD) are two commonly used modes of peritoneal dialysis treatment. APD started late and developed unevenly in China, especially in primary hospitals, and the application rate of APD is lower than CAPD. Based on this background, this study designed a controlled trial to explore the difference of ultrafiltration volume and hospitalization time between APD and CAPD. Finally, 62 patients with end-stage renal disease undergoing maintenance peritoneal dialysis were enrolled and randomly divided into two groups, one group was treated with APD and the other group was treated with CAPD. The results showed that compared with CAPD treatment, APD significantly increased the ultrafiltration volume of patients, especially in patients with low peritoneal solute transport function, compared with those treated with CPAD, and hospitalized patients could achieve therapeutic effect in a shorter time. The results were statistically significant (P < 0.05).
文章引用：黎岚, 张晓艳. APD与CAPD在终末期肾脏病治疗中超滤量的比较[J]. 临床医学进展, 2025, 15(10): 2540-2546. https://doi.org/10.12677/acm.2025.15103041

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