基于机器学习的心血管手术患者术后谵妄预测模型的范围综述
A Scoping Review of Machine Learning-Based Prediction Models for Postoperative Delirium in Cardiovascular Surgery Patients
DOI: 10.12677/ns.2025.1410262, PDF,    科研立项经费支持
作者: 史晓普*:湖州学院生命健康学院,浙江 湖州;魏学军:湖州学院附属南太湖医院重症监护室,浙江 湖州
关键词: 心血管手术术后谵妄机器学习预测模型范围综述Cardiovascular Surgery Postoperative Delirium Machine Learning Prediction Model Scoping Review
摘要: 本研究通过系统分析应用机器学习预测心血管患者术后谵妄的相关文献,对其预测模型的性能进行了评估。本研究共纳入中、英文文献9篇,样本量87~4476。分析结果显示,随机森林模型在众多机器学习算法中预测性能最优,其AUC值达0.92。术后谵妄预测因子覆盖患者基本资料、术前、术中及术后等多方面因素。机器学习预测模型对术后谵妄的发生具有良好的预测价值,然而现有研究存在样本量小,缺乏外部验证及模型可解释性不足等局限性。未来研究需扩大样本量,选择合理预测特征,增强模型的可解释性和临床应用价值。
Abstract: This study systematically analyzed the literature on the application of machine learning in predicting postoperative delirium in cardiovascular patients and evaluated the performance of the prediction models. A total of 9 Chinese and English articles were included, with sample sizes ranging from 87 to 4476. The analysis showed that among various machine learning algorithms, the random forest model had the best prediction performance, with an AUC value of 0.92. The predictors for postoperative delirium covered multiple factors, including patient basic information, preoperative, intraoperative, and postoperative factors. Machine learning prediction models have good predictive value for the occurrence of postoperative delirium. However, existing studies have limitations such as small sample sizes, lack of external validation, and insufficient model interpretability. Future research needs to increase the sample size, select appropriate prediction features, and enhance the interpretability and clinical application value of the models.
文章引用:史晓普, 魏学军. 基于机器学习的心血管手术患者术后谵妄预测模型的范围综述[J]. 护理学, 2025, 14(10): 1959-1966. https://doi.org/10.12677/ns.2025.1410262

参考文献

[1] Pezzella, P. (2022) The ICD‐11 Is Now Officially in Effect. World Psychiatry, 21, 331-332. [Google Scholar] [CrossRef] [PubMed]
[2] Soehle, M., Dittmann, A., Ellerkmann, R.K., Baumgarten, G., Putensen, C. and Guenther, U. (2015) Intraoperative Burst Suppression Is Associated with Postoperative Delirium Following Cardiac Surgery: A Prospective, Observational Study. BMC Anesthesiology, 15, Article No. 61. [Google Scholar] [CrossRef] [PubMed]
[3] Shokhirev, M.N. and Johnson, A.A. (2022) An Integrative Machine-Learning Meta-Analysis of High-Throughput Omics Data Identifies Age-Specific Hallmarks of Alzheimer’s Disease. Ageing Research Reviews, 81, Article ID: 101721. [Google Scholar] [CrossRef] [PubMed]
[4] Sepulveda, E., Franco, J.G., Trzepacz, P.T., Gaviria, A.M., Meagher, D.J., Palma, J., et al. (2016) Delirium Diagnosis Defined by Cluster Analysis of Symptoms versus Diagnosis by DSM and ICD Criteria: Diagnostic Accuracy Study. BMC Psychiatry, 16, Article No. 167. [Google Scholar] [CrossRef] [PubMed]
[5] van der Mast, R.C. (1998) Pathophysiology of Delirium. Journal of Geriatric Psychiatry and Neurology, 11, 138-145. [Google Scholar] [CrossRef] [PubMed]
[6] Hirsch, J., DePalma, G., Tsai, T.T., Sands, L.P. and Leung, J.M. (2015) Impact of Intraoperative Hypotension and Blood Pressure Fluctuations on Early Postoperative Delirium after Non-Cardiac Surgery. British Journal of Anaesthesia, 115, 418-426. [Google Scholar] [CrossRef] [PubMed]
[7] Racine, A.M., Tommet, D., D’Aquila, M.L., Fong, T.G., Gou, Y., Tabloski, P.A., et al. (2020) Machine Learning to Develop and Internally Validate a Predictive Model for Post-Operative Delirium in a Prospective, Observational Clinical Cohort Study of Older Surgical Patients. Journal of General Internal Medicine, 36, 265-273. [Google Scholar] [CrossRef] [PubMed]
[8] Abdar, M., Książek, W., Acharya, U.R., Tan, R., Makarenkov, V. and Pławiak, P. (2019) A New Machine Learning Technique for an Accurate Diagnosis of Coronary Artery Disease. Computer Methods and Programs in Biomedicine, 179, Article ID: 104992. [Google Scholar] [CrossRef] [PubMed]
[9] Li, Y., Xu, J., Wang, Y., Zhang, Y., Jiang, W., Shen, B., et al. (2020) A Novel Machine Learning Algorithm, Bayesian Networks Model, to Predict the High‐Risk Patients with Cardiac Surgery‐associated Acute Kidney Injury. Clinical Cardiology, 43, 752-761. [Google Scholar] [CrossRef] [PubMed]
[10] Yang, T., Yang, H., Liu, Y., Liu, X., Ding, Y., Li, R., et al. (2024) Postoperative Delirium Prediction after Cardiac Surgery Using Machine Learning Models. Computers in Biology and Medicine, 169, Article ID: 107818. [Google Scholar] [CrossRef] [PubMed]
[11] Nowakowska, K., Sakellarios, A., Kaźmierski, J., Fotiadis, D.I. and Pezoulas, V.C. (2023) AI-Enhanced Predictive Modeling for Identifying Depression and Delirium in Cardiovascular Patients Scheduled for Cardiac Surgery. Diagnostics, 14, Article No. 67. [Google Scholar] [CrossRef] [PubMed]
[12] Zhao, X., Li, J., Xie, X., Fang, Z., Feng, Y., Zhong, Y., et al. (2024) Online Interpretable Dynamic Prediction Models for Postoperative Delirium after Cardiac Surgery under Cardiopulmonary Bypass Developed Based on Machine Learning Algorithms: A Retrospective Cohort Study. Journal of Psychosomatic Research, 176, Article ID: 111553. [Google Scholar] [CrossRef] [PubMed]
[13] Mufti, H.N., Hirsch, G.M., Abidi, S.R. and Abidi, S.S.R. (2019) Exploiting Machine Learning Algorithms and Methods for the Prediction of Agitated Delirium after Cardiac Surgery: Models Development and Validation Study. JMIR Medical Informatics, 7, e14993. [Google Scholar] [CrossRef] [PubMed]
[14] Li, Q., Li, J., Chen, J., Zhao, X., Zhuang, J., Zhong, G., et al. (2024) A Machine Learning-Based Prediction Model for Postoperative Delirium in Cardiac Valve Surgery Using Electronic Health Records. BMC Cardiovascular Disorders, 24, Article No. 56. [Google Scholar] [CrossRef] [PubMed]
[15] Nagata, C., Hata, M., Miyazaki, Y., Masuda, H., Wada, T., Kimura, T., et al. (2023) Development of Postoperative Delirium Prediction Models in Patients Undergoing Cardiovascular Surgery Using Machine Learning Algorithms. Scientific Reports, 13, Article No. 21090. [Google Scholar] [CrossRef] [PubMed]
[16] Han, C., Kim, H.I., Soh, S., Choi, J.W., Song, J.W. and Yoon, D. (2024) Machine Learning with Clinical and Intraoperative Biosignal Data for Predicting Postoperative Delirium after Cardiac Surgery. iScience, 27, Article ID: 109932. [Google Scholar] [CrossRef] [PubMed]
[17] 黄琦, 关美娇, 邹彬, 等. 机器学习模型预测心脏外科手术患者术后谵妄的有效性[J]. 临床麻醉学杂志, 2023, 39(4): 363-369.
[18] 左都坤, 吴卓熙, 龙宗泓, 等. 基于机器学习算法构建心脏手术患者术后早期谵妄风险预测模型[J]. 陆军军医大学学报, 2023, 45(8): 753-758.
[19] 伍侨. 老年术后谵妄发生率及危险因素的系统评价[D]: [硕士学位论文]. 成都: 成都中医药大学, 2021.