沙棘脂肪酸修复烧伤的机制及应用
The Mechanism and Application of Sea Buckthorn Fatty Acids in Burn Wound Repair
DOI: 10.12677/acm.2025.15113063, PDF,    科研立项经费支持
作者: 王飞越, 赵丽虹, 邱 佳, 李润佳:内蒙古医科大学第三临床医学院,内蒙古 包头;李 全:内蒙古包钢医院烧伤科,内蒙古 包头;曹晓东:内蒙古医科大学药学院,内蒙古 呼和浩特;张子英, 马月宏*:内蒙古医科大学基础医学院,内蒙古 呼和浩特;韩 帅*:内蒙古医科大学动物实验中心,内蒙古 呼和浩特
关键词: 沙棘脂肪酸烧伤创面愈合联合疗法Sea Buckthorn Fatty Acids Burn Wound Healing Combination Therapy
摘要: 烧伤治疗面临着控制炎症反应、加速创面愈合和减少瘢痕形成等多重挑战。沙棘果实天然脂肪酸复合物通过多靶点作用机制,有抗炎、减轻氧化损伤、抗感染、促进创面愈合与组织再生等作用,对烧伤修复有显著优势,在局部制剂开发及与光疗联合方面也取得较好的应用,在动物试验和临床中得到有效验证。在烧伤治疗领域具有巨大的应用潜力和广阔前景。为创面管理提供了新的生物活性材料选择。
Abstract: Burn treatment faces multiple challenges, such as the control of inflammatory responses, acceleration of wound healing, and reduction of scar formation. The natural fatty acid complex derived from sea buckthorn fruits exerts multiple effects, including anti-inflammation, reduction of oxidative damage, anti-infection, and promotion of wound healing and tissue regeneration via a multi-target mechanism. This multifaceted activity demonstrates significant advantages in burn repair. It has shown promising progress both in the development of topical preparations and in combination with Photo Biomodulation Therapy (PBMT). Its efficacy has been well-documented in both animal experiments and clinical studies. This complex provides a new bioactive material option for wound management and holds great application potential and broad prospects in the field of burn treatment.
文章引用:王飞越, 赵丽虹, 邱佳, 李润佳, 李全, 曹晓东, 张子英, 韩帅, 马月宏. 沙棘脂肪酸修复烧伤的机制及应用[J]. 临床医学进展, 2025, 15(11): 41-49. https://doi.org/10.12677/acm.2025.15113063

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