基于态靶因果理论治疗高血压的研究进展

Research Progress in the Treatment of Hypertension Based on the Theory of State-Target Causality

摘要: 随着生活水平的不断提高，人们的饮食结构也在不断发生变化，高血压病人的数量越来越多。现代医学治疗高血压，常采用抗高血压药物进行治疗，尽管高血压的治疗技术和手段在不断进步，但当前高血压的管理状况仍不容乐观。中医凭借其辨证论治的个体化诊疗思维，以及中药多靶点、整体调节的作用机制，在高血压病的治疗体系中占有一席之地，展现出重要的临床应用价值。仝小林教授于2015年提出了“态靶理论”，后完善为态靶因果。态靶因果理论“以病为纬、以态为经、微观定靶、察因态、重果态”的诊疗策略为临床治疗高血压病这一难题提供了新的思路。在态靶因果理论的指导下，医生在临床实践中也能更灵活地探讨中医药治疗高血压病的症状、证候等方面的机制和效用，把握疾病的核心病机和发展态势，精准用药。提高了临床治疗的有效性和精准性。

Abstract: With the continuous improvement of living standards, people’s dietary structure is constantly changing, and the number of patients with hypertension is increasing. Modern medicine often uses antihypertensive drugs to treat hypertension. Although the treatment techniques and methods for hypertension are constantly improving, the current management situation of hypertension is still not optimistic. Traditional Chinese medicine, with its individualized diagnosis and treatment thinking based on syndrome differentiation and treatment, as well as the multi-target and holistic regulatory mechanism of traditional Chinese medicine, occupies a place in the treatment system of hypertension and demonstrates important clinical application value. Professor Tong Xiaolin proposed the “state-target Theory” in 2015, which was later refined into state-target causality. The diagnosis and treatment strategy of the “state-target causality theory”, which takes disease as the latitude, state as the longitude, micro-level target determination, cause-state observation, and result-state emphasis, provides a new approach for the clinical treatment of hypertension, a difficult problem. Under the guidance of the target-state causality theory, doctors can also more flexibly explore the mechanisms and efficacy of traditional Chinese medicine in treating the symptoms and syndromes of hypertension in clinical practice, grasp the core pathogenesis and development trend of the disease, and use drugs precisely. It has improved the effectiveness and accuracy of clinical treatment.