连续性肾脏替代治疗非计划下机风险预测模型研究进展
Research Progress on Risk Prediction Models for Unplanned Termination of Continuous Renal Replacement Therapy
DOI: 10.12677/acm.2025.15113093, PDF,   
作者: 陈雪巧：赣南医科大学护理学院，江西 赣州；王 芬*, 刘艳秀, 华 莉：赣南医科大学第一附属医院，江西 赣州
关键词: 连续性肾脏替代治疗；非计划下机；风险预测模型；综述；Continuous Renal Replacement Therapy； Unplanned Termination； Risk Prediction Model； Review
摘要: 连续性肾脏替代治疗(CRRT)在重症患者管理中发挥着至关重要的作用。然而，治疗过程中的非计划下机仍是影响患者疗效与预后的关键临床难题。研究表明，非计划下机与患者住院时间延长、病情恶化及死亡率增加密切相关。因此，识别CRRT非计划下机的影响因素并构建预测模型已成为当前的研究热点与临床迫切需求。本文旨在系统综述国内外关于CRRT非计划下机的危险因素及其风险预测模型的相关研究进展。以期为优化CRRT治疗策略、降低非计划下机率提供参考，最终有助于改善患者治疗效果与生存质量。
Abstract: Continuous Renal Replacement Therapy (CRRT) plays an essential role in the management of critically ill patients. Nevertheless, unplanned termination of CRRT remains a significant clinical challenge that adversely affects treatment efficacy and patient prognosis. Evidence indicates that unplanned termination is strongly associated with prolonged hospitalization, disease progression, and increased mortality. Consequently, identifying risk factors associated with unplanned CRRT termination and developing predictive models have emerged as both a research priority and an urgent clinical need. This article systematically reviews recent advances in the study of risk factors and risk prediction models for unplanned CRRT termination, both domestically and internationally. It aims to provide insights for optimizing CRRT treatment strategies, reducing the incidence of unplanned termination, and ultimately improving clinical outcomes and quality of life for patients.
文章引用：陈雪巧, 王芬, 刘艳秀, 华莉. 连续性肾脏替代治疗非计划下机风险预测模型研究进展[J]. 临床医学进展, 2025, 15(11): 260-267. https://doi.org/10.12677/acm.2025.15113093

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