针刺抑制脑出血后铁死亡的研究进展
Research Progress on Acupuncture in Inhibiting Ferroptosis after Intracerebral Hemorrhage
DOI: 10.12677/acm.2025.15113100, PDF,   
作者: 张晓晓：黑龙江中医药大学研究生院，黑龙江 哈尔滨；孔 莹*：黑龙江中医药大学附属第二医院针灸科，黑龙江 哈尔滨
关键词: 脑出血；铁死亡；针刺；综述；Intracerebral Hemorrhage； Ferroptosis； Acupuncture； Review
摘要: 脑出血是神经科常见急重症，致残率、复发率较高。患者脑出血后继发脑损伤是当今临床治疗的难点。研究发现铁死亡在脑出血后继发性损伤中发挥着至关重要的作用。铁死亡是一种铁依赖性的非凋亡细胞死亡方式，其特征为细胞内铁诱导的脂质活性氧积累引起氧化应激造成细胞死亡。本文就铁死亡与脑出血后脑损伤的关系以及针刺治疗的研究进展进行了综述，以期为针刺治疗脑出血后继发性损伤的探索提供参考。
Abstract: Intracerebral hemorrhage (ICH) is a common and severe neurological emergency characterized by high rates of disability and recurrence. Secondary brain injury following ICH remains a significant challenge in contemporary clinical treatment. Research has found that ferroptosis plays a crucial role in the secondary injury after ICH. Ferroptosis is an iron-dependent, non-apoptotic form of cell death characterized by the accumulation of iron-induced lipid reactive oxygen species, leading to oxidative stress and subsequent cell death. This article reviews the relationship between ferroptosis and brain injury after ICH, as well as the research progress in acupuncture treatment, aiming to provide references for exploring acupuncture as a therapeutic approach for secondary injury following ICH.
文章引用：张晓晓, 孔莹. 针刺抑制脑出血后铁死亡的研究进展[J]. 临床医学进展, 2025, 15(11): 314-321. https://doi.org/10.12677/acm.2025.15113100

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