从中医理论探析慢性肾衰竭“夏稳冬重”现象的病机

The Pathogenesis of the Phenomenon of “Summer Stable and Winter Heavy” in Chronic Renal Failure from the Perspective of Traditional Chinese Medicine Theory

摘要: 慢性肾衰竭(Chronic Renal Failure, CRF)作为多种慢性肾脏病进展至终末期的共同结局，具有病程迁延、病情易反复、预后较差的特点。临床观察发现，CRF患者病情存在显著季节差异，多表现为夏季病情相对稳定，冬季则易出现症状加重、肾功能指标恶化及住院率升高。本文基于“天人相应”“整体观念”理论，系统阐述CRF患者“夏稳冬重”现象的内在机理，并结合现代临床研究证据，提出“因时制宜”的防治策略，为临床实践提供理论指导。

Abstract: Chronic Renal Failure (CRF), as a common outcome of a variety of chronic kidney diseases that progress to the end stage, has the characteristics of a prolonged disease course, easy recurrence of disease, and poor prognosis. Clinical observation has found that there are significant seasonal differences in the condition of CRF patients. The condition is usually relatively stable in summer, but symptoms are prone to worsening, renal function indicators worsen, and hospitalization rates increase in winter. Based on the theory of “correspondence between nature and man” and “holistic concept”, this article systematically explains the internal mechanism of the phenomenon of “stable in summer and heavy in winter” in patients with CRF, and combines it with modern clinical research evidence to propose a prevention and treatment strategy that “adapts to current conditions” to provide theoretical guidance for clinical practice.