从络病角度分析阿尔茨海默病发病机制及治疗

Analysis of the Pathogenesis and Treatment of Alzheimer’s Disease from the Perspective of Collateral Disease

摘要: 阿尔茨海默病(AD)在世界范围内发病率高，并持续增长，中国是世界上AD患者最多的国家，也是发病患者数量增长最快的国家。中医可以改善AD患者症状，提升临床综合疗效。络病理论是中医理论的重要组成部分。本文通过阅读古籍和现代文献，分析AD发病与络脉亏虚，络脉淤堵，毒损脑络，而后产生的一系列病理变化有关。现代学者气脉和血脉理论的提出，丰富了AD的络病发病机制理论。本文通过对AD络脉发病机制研究，以期为临床AD的综合康复方案中的中医治疗提供思路。

Abstract: Alzheimer’s Disease (AD) has a high incidence rate worldwide and continues to grow. China has the largest number of AD patients in the world and is also the country with the fastest-growing number of affected patients. Traditional Chinese medicine can improve the symptoms of AD patients and enhance the comprehensive clinical efficacy. The collateral disease theory is an important part of traditional Chinese medicine theory. By reading ancient books and modern literature, this paper analyzes that the pathogenesis of AD is related to a series of pathological changes caused by collateral deficiency, collateral stasis, and toxic damage to brain collaterals. The proposal of the theories of Qi collaterals and blood collaterals by modern scholars has enriched the theory of the pathogenesis of collateral diseases in AD. Through the study on the pathogenesis of AD collaterals, this paper aims to provide ideas for traditional Chinese medicine treatment in the comprehensive rehabilitation program of clinical AD.