基于络病理论探讨迷走神经刺激对房颤的调控机制及中医药治疗进展

Regulatory Mechanisms of Vagus Nerve Stimulation in Atrial Fibrillation: Insights from the Collateral Disease Theory and Advances in Traditional Chinese Medicine

摘要: 房颤(Atrial Fibrillation, AF)是一种常见的心律失常，具有高发病率和高复发率，且常伴随严重并发症。近年来，迷走神经刺激(Vagus Nerve Stimulation, VNS)被提出作为治疗房颤的新兴方法，通过调节自主神经系统对心脏的影响，从而减少房颤的发生。另一方面，中医的络病理论在房颤的病机解释中也具有重要价值，强调“血脉不畅”和“络脉失养”作为疾病的核心病因。本文旨在探讨迷走神经刺激在房颤治疗中的作用机制，并结合中医络病理论，为房颤的治疗提供新的视角和思路。

Abstract: Atrial Fibrillation (AF) is a common arrhythmia with high incidence and recurrence rates, often accompanied by serious complications. In recent years, Vagus Nerve Stimulation (VNS) has been proposed as an emerging method for treating AF. It works by modulating the autonomic nervous system’s influence on the heart, thereby reducing the occurrence of AF. On the other hand, Traditional Chinese Medicine’s (TCM) theory of collateral diseases also holds significant value in explaining the pathogenesis of AF, emphasizing “obstruction of blood vessels” and “nourishment loss of collaterals” as core causes of the disease. This article aims to explore the mechanism of VNS in the treatment of AF and, in combination with TCM’s collateral disease theory, provide new perspectives and approaches for the treatment of AF.