一例哌拉西林钠舒巴坦钠导致头皮瘙痒不良反应的病例分析

Case Analysis of an Adverse Reaction of Scalp Pruritus Caused by Piperacillin Sodium and Sulbactam Sodium

摘要: 哌拉西林钠舒巴坦钠作为特殊使用级抗菌药物，因其克服耐药性及提高患者生存率用于呼吸道、泌尿道、腹腔等常见感染治疗中。但由于个体差异大，易发生各类不良反应，在治疗中需要给予更多的关注。报道1例65岁的女性患者因使用哌拉西林钠舒巴坦钠可能导致的头皮瘙痒，入院后经过改善治疗使症状缓解的病例。另对相关文献资料进行回顾总结，旨在进一步提高临床医师及药师对抗菌药物相关不良反应的认识，增加抗菌药物的临床应用经验。

Abstract: Piperacillin sodium and sulbactam sodium, as special-purpose antibacterial drugs, are used in the treatment of common infections in the respiratory tract, urinary tract, abdominal cavity, etc., due to their ability to overcome drug resistance and improve patient survival rates. However, due to significant individual differences, various adverse reactions are prone to occur, and more attention needs to be paid during treatment. This report presents a case of a 65-year-old female patient whose scalp itching may be caused by taking piperacillin sodium and sulbactam sodium. After admission, her symptoms were relieved through improved treatment. In addition, a review and summary of relevant literature materials were conducted, aiming to further enhance the awareness of clinical physicians and pharmacists regarding adverse reactions related to antibiotics and increase their clinical application experience of antibiotic drugs.