以幽门梗阻为首发症状的系统性轻链型淀粉样变性1例并文献复习
A Case of Light Chain Amyloidosis with Pyloric Obstruction as the Initial Manifestation and Literature Review
DOI: 10.12677/acm.2025.15113211, PDF,   
作者: 刘 雅, 赵文君, 刘爱玲, 丁雪丽, 王小玮, 毛 涛, 刘 华*：青岛大学附属医院消化科，山东 青岛
关键词: 淀粉样变性；幽门梗阻；诊断；治疗；Amyloidosis； Pyloric Obstruction； Diagnosis； Treatment
摘要: 系统性轻链型(systemic light chain, AL)淀粉样变性是指单克隆轻链异常折叠形成的淀粉样蛋白沉积于多种组织器官而导致其功能障碍的一种疾病，可累及心、肝、肾、肺、周围神经、胃肠道及皮肤软组织等多种器官。本病预后不良，且临床表现复杂多样、消化内镜表现缺乏特异性，本文报道1例以幽门梗阻为首发症状的系统性轻链型淀粉样变性1例，以期提高临床医生对此病的认识。
Abstract: Systemic light chain (AL) amyloidosis is a disease in which amyloid protein formed by abnormal folding of monoclonal light chain is deposited in a variety of tissues and organs, resulting in its dysfunction. It can involve a variety of organs such as heart, liver, kidney, lung, peripheral nerves, gastrointestinal tract, skin and soft tissue. The prognosis of this disease is poor, and the clinical manifestations are complex and diverse, and the digestive endoscopy findings are not specific. This paper reports 1 case of systemic light chain amyloidosis with pyloric obstruction as the first symptom, in order to improve the understanding of clinicians.
文章引用：刘雅, 赵文君, 刘爱玲, 丁雪丽, 王小玮, 毛涛, 刘华. 以幽门梗阻为首发症状的系统性轻链型淀粉样变性1例并文献复习[J]. 临床医学进展, 2025, 15(11): 1206-1211. https://doi.org/10.12677/acm.2025.15113211

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