帕金森病相关疲劳的中西医研究进展
Research Progress of Chinese and Western Medicine Treatment of Fatigue in Parkinson’s Disease
DOI: 10.12677/tcm.2025.1411706, PDF,   
作者: 太富鈴：成都中医药大学临床医学院，四川 成都；梁静涛*：成都中医药大学附属医院，四川 成都
关键词: 帕金森病；疲劳；中西医研究；综述；Parkinson’s Disease； Fatigue； Traditional Chinese Medicine and Western Medicine Research； Review
摘要: 帕金森病(Parkinson’s Disease, PD)常见于中老年群体，其病理特征表现为黑质多巴胺能神经元减少甚至缺失，是仅次于阿尔茨海默病的第二大神经系统退行性疾病。在PD的各类症状里，疲劳作为易被疏漏的非运动症状，给患者带来诸多不便，极大地干扰了其生活质量。深入探究帕金森病相关疲劳(Parkinson’s Disease-Related Fatigue, PDF)的发病机制以及探寻其治疗办法意义非凡。中西医对于PDF的发病机制有着截然不同的见解。文章总结近年来国内外对PDF的研究，分别从中医和西医的视角出发，详细阐释其发病机制与相应治疗策略，期望能为后续PDF的深入研究提供有益的参考资料。
Abstract: Parkinson’s Disease (PD) is a common neurodegenerative disorder in middle-aged and elderly populations, pathologically characterized by the reduction or even loss of dopaminergic neurons in the substantia nigra. As the second most prevalent neurodegenerative disease after Alzheimer’s disease, PD presents with a range of symptoms, among which fatigue—a frequently overlooked non-motor symptom—imposes significant burdens on patients and severely compromises their quality of life. Investigating the pathogenesis of Parkinson’s Disease-related Fatigue (PDF) and exploring potential treatments are of great importance. Traditional Chinese Medicine (TCM) and Western medicine hold distinct perspectives on the mechanisms underlying PDF. This article reviews recent domestic and international research on PDF, elucidating its pathogenesis and corresponding therapeutic strategies from both TCM and Western medical perspectives, with the aim of providing valuable references for future in-depth studies on PDF.
文章引用：太富鈴, 梁静涛. 帕金森病相关疲劳的中西医研究进展[J]. 中医学, 2025, 14(11): 4895-4901. https://doi.org/10.12677/tcm.2025.1411706

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