一种含锰钼磷多酸化合物的合成、结构及其性能研究

Synthesis, Structure and Performance of a Manganese-Molybdenum-Molybdenum Phosphorus Polyacid Compound

摘要: 运用水热合成法制备出化合物[(C₄H₉)₄N]₆{[(Mn(C₇H₆N₂)(H₂O)]PMo₁₂O₄₀}₂。通过X-射线单晶衍射仪该化合物的晶体结构予以测定，并对化合物进行了X射线粉末衍射，傅里叶变换红外光谱以及热重分析一系列表征。测试其光催化降解染料性能，实验表明在光照180 min后，30 mg化合物降解罗丹明B的转化率达到99.26%。在光照60 min后，30 mg化合物降解亚甲基蓝的转化率达到99.23%。对其体外抗肿瘤的性能展开测试，针对胃癌细胞，以及AGS肠癌细胞(HCT116、SW480)、肝癌细胞Huh7、人卵巢腺癌细胞SKOV3进行体外抑制作用的探究。经研究发现，该化合物对人结肠癌细胞SW480呈现出最为显著的抑制效果，其IC₅₀值达到41.74 μM。由此可以推断该化合物是一种具有光催化活性和抗肿瘤活性双功能的钼多酸化合物。

Abstract: The compound [(C₄H₉)₄N]₆{[(Mn(C₇H₆N₂)(H₂O)]PMo₁₂O₄₀}₂ was prepared by hydrothermal synthesis. The crystal structure of the compound was determined by X-ray single crystal diffraction, and the compound was characterized by X-ray powder diffraction, Fourier transform infrared spectroscopy and thermogravimetric analysis. The photocatalytic degradation of dye performance was tested, and the experiment showed that the conversion rate of 30 mg compound to degrade rhodamine B reached 99.26% after 180 min of illumination. After 60 min of illumination, the conversion rate of 30 mg compound to degrade methylene blue reached 99.23%. The anti-tumor performance of the company was tested in vitro, and the inhibition effect of gastric cancer cells, AGS intestinal cancer cells (HCT116, SW480), liver cancer cells Huh7, and human ovarian adenocarcinoma cells SKOV3 were explored in vitro. It was found that the compound showed the most significant inhibitory effect on human colon cancer cells SW480, with an IC50 value of 41.74 μM. It can be inferred that this compound is a molybdenum polyacid compound with dual functions of photocatalytic activity and antitumor activity.