CRISPR/Cas9基因编辑技术在鱼类育种中的应用和展望
Application and Prospect of CRISPR/Cas9 Gene-Editing Technology in Fish Breeding
DOI: 10.12677/hjas.2025.1511168, PDF,    科研立项经费支持
作者: 张龙岗*, 王俊鹏, 和 飞, 王锡荣, 刘 飞, 孟庆磊#：山东省淡水渔业研究院，山东 济南
关键词: 基因编辑；CRISPR/Cas9；鱼类；育种；性状；Gene Editing； CRISPR/Cas9； Fish； Breeding； Traits
摘要: 传统育种技术为提高鱼类产量做出了突出贡献。为满足人们对优质蛋白日益增长的需求，亟需应用新技术加速育种进程，以进一步提升鱼类产量。CRISPR/Cas9基因编辑技术在编辑基因方面因具有速度快、成本低、精度高等优点，已成为加快物种遗传改良进程的重要工具。文章介绍了CRISPR/Cas9基因编辑技术的原理，综述了其在鱼类育种中的应用现状和面临的挑战，并展望了未来的发展方向，以期为该技术在鱼类优良性状遗传改良中的应用提供一定参考。
Abstract: Traditional breeding techniques have made outstanding contributions to improving fish yields. To meet the growing demand for high-quality protein, there is an urgent need to apply new technologies to accelerate the breeding process and further increase fish production. The CRISPR/Cas9 gene-editing technology, with advantages such as high speed, low cost, and high precision in gene editing, has become an important tool for accelerating the genetic improvement of species. This article introduces the principle of CRISPR/Cas9 gene-editing technology, reviews its application status and challenges in fish breeding, and looks forward to its future development directions, aiming to provide certain references for the application of this technology in the genetic improvement of excellent traits in fish.
文章引用：张龙岗, 王俊鹏, 和飞, 王锡荣, 刘飞, 孟庆磊. CRISPR/Cas9基因编辑技术在鱼类育种中的应用和展望[J]. 农业科学, 2025, 15(11): 1335-1344. https://doi.org/10.12677/hjas.2025.1511168

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