移植肾功能延迟恢复的防治近5年研究进展
Research Progress in the Prevention and Treatment of Delayed Graft Function after Allogeneic Renal Transplantation in the Past 5 Years
DOI: 10.12677/acm.2025.15113275, PDF,   
作者: 邓 明, 刘 锐, 李 茂, 梁思敏*：重庆医科大学附属第一医院泌尿外科，重庆
关键词: 肾移植；肾功能延迟恢复；合并症；Kidney Transplantation； Delayed Graft Function； Complications
摘要: 肾移植是终末期肾脏病的有效治疗手段，其技术手段不断革新。然而，肾移植术后移植肾功能延迟恢复(Delayed Graft Function, DGF)一直以来都是移植中心面临的重要挑战，对DGF的诊断及其治疗甚至定义都缺乏标准化，其治疗仍无特异性手段，局限于支持治疗。本综述先系统性介绍了关于DGF现有的各种定义及其优缺点，然后概述了DGF发病机制及相关的干预措施、对患者的长短期影响；最后详细介绍了近五年关于其诊断评估、治疗方法的最新进展。
Abstract: Kidney transplantation, as an effective treatment for end-stage renal disease, has seen continuous innovation in its technical methods. However, delayed graft function (DGF) after kidney transplantation has always been a significant challenge faced by transplant centers, with a lack of standardization in the diagnosis, treatment, and even the definition of DGF. Its treatment still lacks specific means and is limited to supportive therapy. This review first introduces the various existing definitions of DGF and their respective advantages and disadvantages. It then outlines the pathogenesis of DGF, related intervention measures, and their short- and long-term effects on patients. Lastly, it provides a detailed overview of the latest advancements in diagnosis, evaluation, and treatment methods over the past five years.
文章引用：邓明, 刘锐, 李茂, 梁思敏. 移植肾功能延迟恢复的防治近5年研究进展[J]. 临床医学进展, 2025, 15(11): 1733-1741. https://doi.org/10.12677/acm.2025.15113275

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