桃红四物汤治疗桡骨远端骨折术后早期的微观机制：基于血液流变学的视角

Microscopic Mechanism of Taohong Siwu Decoction in the Early Postoperative Period of Distal Radius Fracture: From the Perspective of Hemorheology

摘要: 桃红四物汤作为中医活血化瘀的代表方剂，在桡骨远端骨折术后早期的临床应用显示出了显著疗效。本文从微观视角，特别是血液流变学方向，系统综述了桃红四物汤治疗桡骨远端骨折术后早期的作用机制。通过分析近年来相关临床研究及基础实验发现，桃红四物汤能够有效改善骨折术后局部血液流变学状态，降低全血黏度、血浆黏度及红细胞聚集性，优化局部微循环灌注，从而减轻术后肿胀疼痛，促进骨折愈合。本综述还强调了该领域研究的创新性及未来发展方向，为桃红四物汤在骨折术后治疗的深入研究和临床应用提供了理论依据。

Abstract: Taohong Siwu Decoction, a representative prescription for promoting blood circulation and removing blood stasis in Traditional Chinese Medicine (TCM), has shown significant efficacy in clinical application during the early postoperative period of distal radius fracture. From a microscopic perspective, especially focusing on hemorheology, this article systematically reviews the mechanism of action of Taohong Siwu Decoction in the early postoperative treatment of distal radius fracture. By analyzing relevant clinical studies and basic experiments in recent years, it has been found that Taohong Siwu Decoction can effectively improve the local hemorheological state after fracture surgery, reduce whole blood viscosity, plasma viscosity and red blood cell aggregation, and optimize local microcirculation perfusion. These effects further alleviate postoperative swelling and pain, and promote fracture healing. This review also emphasizes the innovation of research in this field and future development directions, providing a theoretical basis for the in-depth research and clinical application of Taohong Siwu Decoction in postoperative fracture treatment.