基于“脾藏意”理论浅谈肠道菌群与认知功能障碍的病因病机
A Preliminary Discussion on the Etiology and Pathogenesis of Intestinal Flora and Cognitive Dysfunction Based on the Theory of “Spleen Storing Ideation Yi”
摘要: 肠道菌群对认知能力障碍的形成和进展具有显著影响。研究指出，调整肠道微生物群有助于缓解痴呆症的表现。传统中医学中的“脾胃”可类比肠道菌群在人体生命活动中生理及病理方面所发挥作用，通过调理脾胃来改善认知障碍的有效性已得到验证。截至当前，研究人员正处于初步阶段，利用中医药调整肠道菌群以预防和治疗痴呆症。本研究旨在通过调节肠道菌群，以传统医学脾胃生理病理特性为切入点，探索治疗认知障碍的机制，进而为认知功能障碍的干预提供新的思路。
Abstract: Intestinal flora has a significant impact on the formation and progression of cognitive impairment. Research has indicated that adjusting the intestinal microbiota can help alleviate the manifestations of dementia. In Traditional Chinese Medicine (TCM), the concept of “spleen and stomach” can be analogized to the physiological and pathological roles played by intestinal flora in human life activities. The effectiveness of regulating the spleen and stomach to improve cognitive impairment has been verified. To date, researchers are in the preliminary stages of utilizing traditional Chinese medicine to adjust intestinal flora for the prevention and treatment of dementia. This study aims to explore the mechanisms of treating cognitive impairment by regulating intestinal flora, using the physiological and pathological characteristics of the spleen and stomach in traditional medicine as an entry point, thereby providing new insights for the intervention of cognitive dysfunction.
文章引用：庄佳美, 张民. 基于“脾藏意”理论浅谈肠道菌群与认知功能障碍的病因病机 [J]. 中医学, 2025, 14(11): 5100-5104. https://doi.org/10.12677/tcm.2025.1411734

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