风湿免疫疾病相关不明原因发热的诊治进展
Advances in the Diagnosis and Treatment of Fever of Unknown Origin Related to Rheumatic and Autoimmune Diseases
摘要: 不明原因发热(FUO)在临床上相当常见，没有特异性的临床表现和体征，经常规的实验室检测和影像学检查仍不能明确病因。感染性疾病、非感染性炎症性疾病和肿瘤性疾病是导致FUO的主要原因，近年来，风湿免疫疾病在FUO中的比例明显上升，但是，由于风湿免疫疾病临床表现复杂多样、病程反复迁延、免疫学特征多样以及部分地区检测技术的局限性使其容易被误诊或漏诊，所以早期精准识别风湿免疫疾病相关FUO并进行诊治就显得十分必要。本文通过检索国内外的文献，对风湿免疫疾病相关FUO的特征与诊治进展做一综述。
Abstract: Fever of unknown origin (FUO) is fairly common in clinical practice. It lacks specific clinical manifestations and signs, and routine laboratory tests and imaging examinations often fail to clarify the cause. Infectious diseases, non-infectious inflammatory diseases, and neoplastic diseases are the main causes of FUO. In recent years, the proportion of FUO caused by rheumatic and autoimmune diseases has significantly increased. However, due to the complex and diverse clinical manifestations, recurrent and prolonged course, varied and heterogeneous immunological features and the limitations of diagnostic techniques in some regions, these conditions are easily misdiagnosed or overlooked. Therefore, early and precise identification and management of FUO related to rheumatic and autoimmune diseases is essential. This article reviews the advances in the diagnosis and treatment of FUO related to rheumatic and autoimmune diseases based on domestic and international literature.
文章引用：丁文亮, 唐琳. 风湿免疫疾病相关不明原因发热的诊治进展[J]. 临床医学进展, 2025, 15(11): 2016-2022. https://doi.org/10.12677/acm.2025.15113314

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