慢性创面渗液管理及收湿敛疮类外用中药的研究进展

Research Progress on the Management of Chronic Wound Exudate and the Application of Collecting Dampness and Healing Sores Chinese Herbal Medicines

摘要: 收湿敛疮类外用药物是慢性难愈合伤口治疗中必不可少的一部分，在治疗外科疾病中发挥着十分积极的作用。由于慢性难愈合伤口长期炎症浸润，组织液渗出，同时伴随细菌、真菌等感染，渗液管理尤为重要。目前临床上常用到的有各种敷料，吸收渗液并能为创面提供良好的愈合环境促进愈合，也有各种新型技术收纳渗液。本文结合国内外相关研究，将目前外用的更好管理慢性难愈合伤口渗液的外用药物统称为收湿敛疮类外用药物，分别从敷料、技术、药物这几个方面对收湿敛疮进行探讨，为收湿敛疮类外用药物的临床应用和药物开发提供新的思路。

Abstract: External medications for treating chronic and difficult-to-heal wounds, such as those used to absorb dampness and relieve sores, play an essential role in the treatment of surgical diseases. Due to the long-term inflammatory infiltration and tissue fluid leakage of chronic and difficult to heal wounds, accompanied by bacterial, fungal and other infections, exudate management is particularly important. At present, various dressings are commonly used in clinical practice, which can absorb exudate and provide a good healing environment for wounds to promote healing. There are also various new technologies for storing exudate. This article combines relevant research at home and abroad to collectively refer to the topical drugs that are currently used for better management of chronic difficult-to-heal wound exudate as dampness-reducing and ulcer-healing topical drugs. It discusses dampness-reducing and ulcer-healing topical drugs from the aspects of dressings, techniques, and drugs, providing new ideas for the clinical application and drug development of dampness-reducing and ulcer-healing topical drugs.