基于正交试验的离心式人工心脏泵叶片参数优化
Parameter Optimization of Centrifugal Artificial Heart Pump Blade Based on Orthogonal Test
DOI: 10.12677/hjbm.2025.156125, PDF,    国家自然科学基金支持
作者: 孙丽颖：上海理工大学东方泛血管器械创新学院，上海；穆璐璐, 肖 媛, 吴小龙, 崔国民*：上海理工大学能源与动力工程学院，上海
关键词: 人工心脏泵；叶片参数；正交试验法；水力性能；溶血性能；Artificial Heart Pump； Blade Parameters； Orthogonal Test Method； Hydraulic Performance； Hemolytic Properties
摘要: 评价离心式人工心脏泵的性能主要通过水力特性和溶血特性两方面。为了在离心式人工心脏泵实验研究基础上，探究叶片参数变化对性能的影响，并优化离心式人工心脏泵的性能。通过正交试验设计的方法，选取叶片转速、叶片数量、叶片出口角度和叶片厚度4个因素为变量，以人工心脏泵扬程、效率和剪切应力三个作为离心式人工心脏泵的评价指标，分析各因素对评价指标的影响以及影响的显著度，同时探究出最优的叶片参数组合。研究结果表明，相较于原始的实验数据，更优的叶片参数组合为：转速5000 r/min、叶轮数为4个、出口角度40˚、叶片厚度0.6 mm。验证最优结构的性能：扬程1.14 m、效率22%、剪切应力358.68 Pa。优化后的结构与原模型相比，水力性能和溶血性能更优，同时扬程满足人体的供血需求。
Abstract: The performance of centrifugal artificial heart pumps is mainly evaluated through two aspects: hydraulic characteristics and hemolysis characteristics. In order to explore the impact of blade parameter changes on performance and optimize the performance of centrifugal artificial heart pumps based on experimental research. By using the method of orthogonal experimental design, four factors, namely blade speed, blade quantity, blade outlet angle, and blade thickness, were selected as variables. The head, efficiency, and shear stress of the centrifugal artificial heart pump were used as evaluation indicators. The influence of each factor on the evaluation indicators and their significance were analyzed, and the optimal combination of blade parameters was explored. The research results indicate that compared to the original experimental data, the optimal combination of blade parameters is: speed of 5000 r/min, 4 impellers, outlet angle of 40˚, and blade thickness of 0.6 mm. Verify the performance of the optimal structure: head 1.14 m, efficiency 22%, shear stress 358.68 Pa. Compared with the original model, the optimized structure has better hydraulic and hemolytic performance, while the head meets the blood supply needs of the human body.
文章引用：孙丽颖, 穆璐璐, 肖媛, 吴小龙, 崔国民. 基于正交试验的离心式人工心脏泵叶片参数优化[J]. 生物医学, 2025, 15(6): 1159-1174. https://doi.org/10.12677/hjbm.2025.156125

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