趋化因子样受体1在代谢相关疾病中的研究进展
Progress on Chemokine-Like Receptor 1 in Metabolic Diseases
DOI: 10.12677/acm.2025.15123387, PDF,    科研立项经费支持
作者: 龙 均, 王先耀, 字 颖:大理大学临床医学院,云南 大理;龙 艳:重庆市人民医院心血管内科,重庆;施荣杰*:大理大学第一附属医院消化内科,云南 大理
关键词: 趋化因子样受体1肥胖代谢综合征糖尿病动脉粥样硬化Chemokine-Like Receptor 1 Obesity Metabolic Syndrome Diabetes Atherosclerosis
摘要: 趋化因子样受体1 (CMKLR1)是一种由多种组织与细胞合成并分泌的重要脂肪因子,在免疫与代谢稳态调节中扮演关键角色。其表达水平升高会增加肥胖、糖尿病、脂肪肝等代谢性疾病的发生风险。本文系统综述CMKLR1在代谢性疾病中的作用机制与研究进展,并探讨其作为疾病防治新靶点的潜力。
Abstract: Chemokine-like receptor 1 (CMKLR1) is a critical adipokine produced and released by various tissues and cells. It plays a key role in regulating immune and metabolic homeostasis. Elevated expression levels of CMKLR1 are associated with an increased risk of metabolic diseases, including obesity, diabetes, and fatty liver. This article systematically reviews the mechanisms and research advancements of CMKLR1 in metabolic diseases and discusses its potential as a novel target for disease prevention and treatment.
文章引用:龙均, 龙艳, 王先耀, 字颖, 施荣杰. 趋化因子样受体1在代谢相关疾病中的研究进展[J]. 临床医学进展, 2025, 15(12): 117-124. https://doi.org/10.12677/acm.2025.15123387

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