不同组学在胰腺炎中的应用
Applications of Various Omics in Pancreatitis
摘要: 胰腺炎是常见的消化系统疾病，主要有急性胰腺炎和慢性胰腺炎。急性胰腺炎起病急、进展快、早期诊断困难；慢性胰腺炎则迁延不愈，常伴随多种并发症，临床处理困难。这些疾病造成了沉重的医疗负担。随着基因组学、蛋白质组学和代谢组学等前沿技术的发展，人们对胰腺炎的发生机制、早期诊断和个体化治疗等方面有了更深入的认识。本文旨在叙述近年来多种组学技术在急性胰腺炎、慢性胰腺炎临床应用中的最新进展，以期为该类疾病的机制研究与临床防治提供新的理论依据和未来方向。
Abstract: Pancreatitis is a prevalent digestive disorder with significant clinical implications, primarily classified into acute and chronic forms. Acute pancreatitis (AP) presents with sudden onset, rapid progression, and considerable challenges in early diagnosis. In contrast, chronic pancreatitis (CP) is characterized by its persistent nature and is frequently associated with severe complications, rendering its clinical management particularly complex. These conditions collectively represent a substantial burden on global healthcare systems. With the development of cutting-edge technologies such as genomics, proteomics, and metabolomics, our understanding of the pathogenesis, early diagnosis, and personalized treatment of pancreatitis has deepened. This article aims to describe the latest progress in the clinical application of various omics technologies in acute and chronic pancreatitis, in order to provide a new theoretical basis and future directions for the study of the mechanisms and clinical prevention and treatment of these diseases.
文章引用：邹雨莲, 张月荣. 不同组学在胰腺炎中的应用[J]. 临床医学进展, 2025, 15(12): 143-151. https://doi.org/10.12677/acm.2025.15123390

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