慢性意识障碍患者多模态评估及无创神经调控的研究进展
Research Advances in Multimodal Assessment and Noninvasive Neuromodulation for Prolonged Disorders of Consciousness
DOI: 10.12677/acm.2025.15123428, PDF,    科研立项经费支持
作者: 叶天凤, 刘一玮, 刘思贝, 田 伟, 张渝佳, 孔渝菡*：重庆医科大学附属第一医院康复医学科，重庆；重庆市卫生健康委员会物理医学与精准康复重点实验室，重庆
关键词: 慢性意识障碍；多模态评估；无创神经调控；Prolonged Disorders of Consciousness； Multimodal Assessment； Noninvasive Neuromodulation
摘要: 严重脑损伤后意识丧失超过28天可发展为慢性意识障碍，该病的临床治疗一直是神经康复领域亟待突破的重要难题。近年来多模态评估与无创神经调控技术逐渐成为研究热点。本文旨在从行为学、神经影像学、神经电生理方面综述慢性意识障碍患者的多模态评估的最新研究进展，同时探讨基于磁场、电场和声学物理机制的无创神经调控最新治疗技术，为慢性意识障碍患者的诊疗方案提供理论依据和临床参考。
Abstract: Persistent unresponsiveness lasting more than 28 days following severe brain injury may progress to a prolonged disorder of consciousness. The clinical management of this condition remains a critical challenge requiring breakthroughs in the field of neurorehabilitation. In recent years, multimodal assessment and noninvasive neuromodulation techniques have emerged as key research focuses. This review aims to summarize multimodal assessment methods and noninvasive neuromodulation treatment strategies for patients with disorders of consciousness, to provide theoretical foundations and clinical references to enhance the efficacy and safety of diagnosis and treatment.
文章引用：叶天凤, 刘一玮, 刘思贝, 田伟, 张渝佳, 孔渝菡. 慢性意识障碍患者多模态评估及无创神经调控的研究进展[J]. 临床医学进展, 2025, 15(12): 419-427. https://doi.org/10.12677/acm.2025.15123428

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