1,3-二烯立体选择性合成研究进展
Research Progress in Stereoselective Synthesis of 1,3-Dienes
DOI: 10.12677/jocr.2025.134035, PDF,   
作者: 崔 傲, 侯嘉宁, 何以立：浙江师范大学，化学与材料科学学院，浙江 金华
关键词: 1；3-二烯；立体选择性合成；有机催化；1；3-Dienes； Stereoselective Synthesis； Organocatalysis
摘要: 1,3-丁二烯结构单元广泛存在于许多具有重要生物活性的天然产物和药物分子中。此外，二烯类化合物因其能够实现多种官能团转化(包括各类碳–碳键形成反应)而成为合成化学中的重要中间体。因此，在过去数十年间，二烯的立体选择性合成一直备受关注，诸多新型合成策略不断涌现。本综述系统总结了1,3-二烯立体选择性合成领域的研究进展。
Abstract: The 1,3-butadiene motif is widely found in many natural products and drug candidates with relevant biological activities. Moreover, dienes serve as crucial intermediates in synthetic chemistry, due to their ability to give access to a wide range of functional group transformations, including a broad range of C-C bond-forming processes. Therefore, the stereoselective preparation of dienes has attracted much attention over the past decades, and the search for new synthetic protocols continues unabated. The aim of this review is to give an overview of the research progress in stereoselective synthesis of 1,3-dienes.
文章引用：崔傲, 侯嘉宁, 何以立. 1,3-二烯立体选择性合成研究进展[J]. 有机化学研究, 2025, 13(4): 358-371. https://doi.org/10.12677/jocr.2025.134035

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