瘢痕疙瘩的临床药物治疗现状
Current Status of Clinical Drug Therapy for Keloids
DOI: 10.12677/acm.2025.15123509, PDF,   
作者: 刘文军*, 王 旗, 王 媛, 武孔佳:昆明医科大学第二附属医院烧伤科,云南 昆明
关键词: 瘢痕治疗瘢痕疙瘩药物治疗Scar Treatment Keloid Drug Therapy
摘要: 瘢痕疙瘩作为一种病理性皮肤改变,其形成机制主要涉及成纤维细胞异常增殖以及创伤后胶原蛋白合成失调,最终导致局部组织过度增生。该疾病的治疗具有周期长、难度大的特点,通常需要采用多模式联合治疗方案。然而,即便采用综合治疗手段,患者的复发率仍然居高不下。在瘢痕疙瘩的临床治疗中,药物治疗占据重要地位,目前已有多种治疗策略可供选择。随着研究的深入,传统药物和创新疗法均取得了显著进展,涌现出诸多具有临床应用前景的治疗方案。基于现有研究进展,本文将对瘢痕疙瘩的药物治疗策略进行系统性综述。
Abstract: Keloids, as a pathological skin alteration, are primarily caused by abnormal proliferation of fibroblasts and dysregulated collagen synthesis after injury, ultimately leading to excessive local tissue growth. The treatment of this disease is characterized by long duration and great difficulty, often requiring multi-modal combination therapy. However, even with comprehensive treatment approaches, the recurrence rate remains high. In the clinical management of keloids, drug therapy plays an important role, and various treatment strategies are currently available. With ongoing research, both traditional drugs and innovative therapies have achieved significant progress, with many treatment options showing promising clinical potential. Based on the current research progress, this article provides a systematic review of drug therapy strategies for keloids.
文章引用:刘文军, 王旗, 王媛, 武孔佳. 瘢痕疙瘩的临床药物治疗现状[J]. 临床医学进展, 2025, 15(12): 1102-1110. https://doi.org/10.12677/acm.2025.15123509

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