无创迷走神经电刺激治疗在偏头痛及抑郁障碍中的应用
Application of Non-Invasive Vagus Nerve Stimulation in the Treatment of Migraine and Depressive Disorders
DOI: 10.12677/acm.2025.15123514, PDF,    科研立项经费支持
作者: 蔡青青*, 廖金成, 马璟曦#：重庆医科大学，重庆；重庆市人民医院神经内科，重庆；康富丽, 王 怡, 张晖集：重庆医科大学，重庆；薛锐灵：重庆医科大学，重庆；重庆市人民医院康复医学科，重庆；李 鑫：重庆市沙坪坝区人民医院神经内科，重庆
关键词: 偏头痛；抑郁障碍；无创迷走神经刺激；经皮耳穴迷走神经刺激；经皮颈部迷走神经刺激；Migraine； Depressive Disorder； Noninvasive Vagus Nerve Stimulation (nVNS)； Transcutaneous Auricular Vagus Nerve Stimulation； Transcutaneous Cervical Vagus Nerve Stimulation
摘要: 偏头痛和抑郁障碍都是严重影响患者生存质量的神经精神系统疾病，对个人和社会都造成不小的负担。本文主要概述了偏头痛与抑郁障碍之间的相关关系，无创迷走神经刺激(Noninvasive vagus nerve stimulation, nVNS)的发展进程，然后综述了nVNS在分别治疗和预防偏头痛和抑郁障碍方面的应用。nVNS能够通过影响疼痛调控通路、默认模式网络等脑区从而缓解偏头痛和抑郁障碍进展。虽然nVNS技术在治疗偏头痛和抑郁障碍方面具有显著疗效和安全性，但仍需进行更多的研究来证实其临床应用价值。
Abstract: Both migraine and depressive disorder are neuropsychiatric disorders that seriously affect patients’ quality of life, imposing a considerable burden on individuals and society. This article primarily outlines the correlation between migraine and depressive disorder, the development process of Noninvasive Vagus Nerve Stimulation (nVNS), and then reviews the application of nVNS in the treatment and prevention of migraine and depressive disorder respectively. nVNS can alleviate the progression of migraine and depressive disorder by influencing brain regions, such as pain regulatory pathways and the default mode network. Although nVNS technology exhibits significant efficacy and safety in the treatment of migraine and depressive disorder, more studies are still needed to verify its clinical application value.
文章引用：蔡青青, 康富丽, 王怡, 廖金成, 薛锐灵, 李鑫, 张晖集, 马璟曦. 无创迷走神经电刺激治疗在偏头痛及抑郁障碍中的应用[J]. 临床医学进展, 2025, 15(12): 1146-1155. https://doi.org/10.12677/acm.2025.15123514

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