吲嗪类化合物的合成进展研究
Research Progress in Synthesis of Indolizine Compounds
DOI: 10.12677/jocr.2025.134039, PDF,   
作者: 相李奎, 季江凯:东力(南通)化工有限公司研发中心,江苏 南通;李鹏鹏:洋口镇人民政府生态环境局,江苏 南通
关键词: 吲嗪衍生物环加成反应杂环构筑Indolizine Derivatives Cycloaddition Reaction Heterocycle Construction
摘要: 吲嗪是一种含有氮元素的杂环化合物,具有很强的芳香性,其分子结构中存在一个离域的10π电子体系。基于吲嗪骨架合成的分子,广泛应用于医药、农药和有机材料等领域。2010年以来,化学家们发表的关于吲哚嗪骨架合成的论文已超过100篇,在本文中对近年来合成吲嗪类化合物的方法进行了总结和归纳,为探索构建含氮杂环化合物的新反应途径提供参考价值。
Abstract: Indolizine is a nitrogen-containing heterocycle with strong aromaticity, possessing a delocalized 10π-electron system. Molecules synthesized based on the indolizine skeleton are widely used in fields, such as medicine, pesticides, and organic materials. Since 2010, chemists have published more than 100 papers on the synthesis of indolizine skeletons. This article summarizes and concludes the methods for synthesizing indolizine compounds in recent years, providing reference value for exploring new reaction pathways for constructing nitrogen-containing heterocyclic compounds.
文章引用:相李奎, 李鹏鹏, 季江凯. 吲嗪类化合物的合成进展研究[J]. 有机化学研究, 2025, 13(4): 403-411. https://doi.org/10.12677/jocr.2025.134039

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