全身炎症标志物在结直肠癌预后中的研究进展
Research Progress of Systemic Inflammatory Markers in the Prognosis of Colorectal Cancer
摘要: 本文综述了全身炎症标志物在结直肠癌(Colorectal Cancer, CRC)预后评估中的研究进展。结直肠癌是全球常见的恶性肿瘤，预后评估对治疗决策至关重要。近年来，全身炎症反应被证实与肿瘤的发生发展密切相关，多种炎症标志物作为预后指标受到广泛关注。本文系统介绍了C反应蛋白、中性粒细胞/淋巴细胞比值、血小板/淋巴细胞比值、全身免疫炎症指数等主要炎症标志物的特性、检测方法及其在结直肠癌预后中的应用。通过对比分析各标志物的优缺点，探讨了其在临床应用中的价值与局限，为未来研究方向的确定提供了理论依据。
Abstract: This article reviews the research progress of systemic inflammatory markers in the prognosis assessment of colorectal cancer. Colorectal cancer is a common malignant tumor worldwide, and prognosis assessment is crucial for treatment decisions. In recent years, systemic inflammatory responses have been confirmed to be closely related to the occurrence and development of tumors, and multiple inflammatory markers have received extensive attention as prognostic indicators. This article systematically introduces the characteristics, detection methods, and application in prognosis assessment of major inflammatory markers such as C-reactive protein, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and systemic immune-inflammatory index. By comparing and analyzing the advantages and disadvantages of each marker, the value and limitations in clinical application are discussed, providing a theoretical basis for determining future research directions.
文章引用：汪宇婷, 李航宇, 田明. 全身炎症标志物在结直肠癌预后中的研究进展[J]. 临床医学进展, 2025, 15(12): 1547-1554. https://doi.org/10.12677/acm.2025.15123563

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