MHR和SII在心血管疾病领域的研究进展
Research Advances in MHR and SII in the Field of Cardiovascular Diseases
DOI: 10.12677/acm.2025.15123590, PDF,   
作者: 陈华宇, 马鸿雁*, 郑士玉:北华大学附属医院心血管内科,吉林 吉林
关键词: MHRSII心血管疾病MHR SII Cardiovascular Disease
摘要: 心血管疾病(cardiovascular disease, CVD)主要包括冠心病、高血压、心力衰竭等,是我国居民首位死亡原因。随着我国经济社会的发展和人口老龄化的加剧,心血管疾病患病率持续上升。据推算,CVD现患人数已达3.3亿,已成为严重的社会公共卫生问题。单核细胞与高密度脂蛋白胆固醇比值(mononuclear cell high-density lipoprotein ratio, MHR)和系统免疫炎症指数(systemic immune inflammation index, SII)作为新兴的炎症标志物,在心血管疾病的风险评估、预后预测及治疗指导中展现出重要价值。本文系统综述了MHR与SII在心血管疾病中的研究现状、热点争议及未来发展方向。
Abstract: Cardiovascular disease (CVD), primarily encompassing coronary heart disease, hypertension, and heart failure, ranks as the leading cause of death among Chinese residents. With China’s socioeconomic development and accelerating population aging, the prevalence of CVD continues to rise. Estimates indicate that the current CVD prevalence has reached 330 million individuals, posing a severe public health challenge. The mononuclear cell high-density lipoprotein ratio (MHR) and systemic immune inflammation index (SII), as emerging inflammatory biomarkers, demonstrate significant value in CVD risk assessment, prognosis prediction, and treatment guidance. This systematic review summarizes the current research status, key controversies, and future development directions of MHR and SII in cardiovascular disease.
文章引用:陈华宇, 马鸿雁, 郑士玉. MHR和SII在心血管疾病领域的研究进展[J]. 临床医学进展, 2025, 15(12): 1756-1764. https://doi.org/10.12677/acm.2025.15123590

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