|
[1]
|
Granata, V., Fusco, R., Catalano, O., Setola, S.V., de Lutio di Castelguidone, E., Piccirillo, M., et al. (2016) Multidetector Computer Tomography in the Pancreatic Adenocarcinoma Assessment: An Update. Infectious Agents and Cancer, 11, Article No. 57. [Google Scholar] [CrossRef] [PubMed]
|
|
[2]
|
Pergolizzi, R.G. and Brower, S.T. (2024) Molecular Targets for the Diagnosis and Treatment of Pancreatic Cancer. International Journal of Molecular Sciences, 25, Article No. 10843. [Google Scholar] [CrossRef] [PubMed]
|
|
[3]
|
Zeng, H., Zheng, R., Sun, K., Zhou, M., Wang, S., Li, L., et al. (2024) Cancer Survival Statistics in China 2019-2021: A Multicenter, Population-Based Study. Journal of the National Cancer Center, 4, 203-213. [Google Scholar] [CrossRef] [PubMed]
|
|
[4]
|
Spiliopoulos, S., Reppas, L., Filippiadis, D., Delvecchio, A., Conticchio, M., Memeo, R., et al. (2023) Irreversible Electroporation for the Management of Pancreatic Cancer: Current Data and Future Directions. World Journal of Gastroenterology, 29, 223-231. [Google Scholar] [CrossRef] [PubMed]
|
|
[5]
|
Tiwari, P.K., Shanmugam, P., Karn, V., Gupta, S., Mishra, R., Rustagi, S., et al. (2024) Extracellular Vesicular miRNA in Pancreatic Cancer: From Lab to Therapy. Cancers, 16, Article No. 2179. [Google Scholar] [CrossRef] [PubMed]
|
|
[6]
|
Yang, Y., Shi, X., Chen, G. and Qian, L. (2023) Risk Factors for Unresectable Pancreatic Cancer Following High‐Intensity Focused Ultrasound Treatment. Cancer Medicine, 12, 19537-19547. [Google Scholar] [CrossRef] [PubMed]
|
|
[7]
|
Yan, B.M. and Myers, R.P. (2007) Neurolytic Celiac Plexus Block for Pain Control in Unresectable Pancreatic Cancer. The American Journal of Gastroenterology, 102, 430-438. [Google Scholar] [CrossRef] [PubMed]
|
|
[8]
|
Hameed, M., Hameed, H. and Erdek, M. (2010) Pain Management in Pancreatic Cancer. Cancers, 3, 43-60. [Google Scholar] [CrossRef] [PubMed]
|
|
[9]
|
Bapat, A.A., Hostetter, G., Von Hoff, D.D. and Han, H. (2011) Perineural Invasion and Associated Pain in Pancreatic Cancer. Nature Reviews Cancer, 11, 695-707. [Google Scholar] [CrossRef] [PubMed]
|
|
[10]
|
di Mola, F.F. and di Sebastiano, P. (2008) Pain and Pain Generation in Pancreatic Cancer. Langenbeck’s Archives of Surgery, 393, 919-922. [Google Scholar] [CrossRef] [PubMed]
|
|
[11]
|
D’Haese, J.G., Hartel, M., Demir, I.E., Hinz, U., Bergmann, F., Büchler, M.W., et al. (2014) Pain Sensation in Pancreatic Diseases Is Not Uniform: The Different Facets of Pancreatic Pain. World Journal of Gastroenterology, 20, 9154-9161.
|
|
[12]
|
Chen, C.K. and Erdek, M.A. (2025) Celiac Plexus Block and Neurolysis Procedure: Treatment of Chronic Pain in Pancreatic Cancer. Pain Management, 15, 779-781. [Google Scholar] [CrossRef]
|
|
[13]
|
Sachdev, A.H. and Gress, F.G. (2018) Celiac Plexus Block and Neurolysis: A Review. Gastrointestinal Endoscopy Clinics of North America, 28, 579-586. [Google Scholar] [CrossRef] [PubMed]
|
|
[14]
|
Furness, J.B., Callaghan, B.P., Rivera, L.R. and Cho, H. (2014) The Enteric Nervous System and Gastrointestinal Innervation: Integrated Local and Central Control. In: Lyte, M. and Cryan, J.F., Eds., Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease, Springer, 39-71. [Google Scholar] [CrossRef] [PubMed]
|
|
[15]
|
Barreto, S.G. and Saccone, G.T.P. (2012) Pancreatic Nociception—Revisiting the Physiology and Pathophysiology. Pancreatology, 12, 104-112. [Google Scholar] [CrossRef] [PubMed]
|
|
[16]
|
Ceyhan, G.O., Bergmann, F., Kadihasanoglu, M., Altintas, B., Demir, I.E., Hinz, U., et al. (2009) Pancreatic Neuropathy and Neuropathic Pain—A Comprehensive Pathomorphological Study of 546 Cases. Gastroenterology, 136, 177-186.e1. [Google Scholar] [CrossRef] [PubMed]
|
|
[17]
|
Lohse, I. and Brothers, S.P. (2020) Pathogenesis and Treatment of Pancreatic Cancer Related Pain. Anticancer Research, 40, 1789-1796. [Google Scholar] [CrossRef] [PubMed]
|
|
[18]
|
Lahoud, M.J., Kourie, H.R., Antoun, J., Osta, L.E. and Ghosn, M. (2016) Road Map for Pain Management in Pancreatic Cancer: A Review. World Journal of Gastrointestinal Oncology, 8, 599-606. [Google Scholar] [CrossRef] [PubMed]
|
|
[19]
|
Warshaw, A.L., Banks, P.A. and Fernàndez-del Castillo, C. (1998) AGA Technical Review: Treatment of Pain in Chronic Pancreatitis. Gastroenterology, 115, 765-776. [Google Scholar] [CrossRef] [PubMed]
|
|
[20]
|
Aprile, G., Rihawi, K., De Carlo, E. and Sonis, S.T. (2015) Treatment-Related Gastrointestinal Toxicities and Advanced Colorectal or Pancreatic Cancer: A Critical Update. World Journal of Gastroenterology, 21, 11793-11803. [Google Scholar] [CrossRef] [PubMed]
|
|
[21]
|
Coveler, A.L., Mizrahi, J., Eastman, B., Apisarnthanarax, S., Dalal, S., McNearney, T., et al. (2021) Pancreas Cancer-Associated Pain Management. The Oncologist, 26, e971-e982. [Google Scholar] [CrossRef] [PubMed]
|
|
[22]
|
Bunchorntavakul, C. and Reddy, K.R. (2013) Acetaminophen-Related Hepatotoxicity. Clinics in Liver Disease, 17, 587-607. [Google Scholar] [CrossRef] [PubMed]
|
|
[23]
|
Corder, G., Castro, D.C., Bruchas, M.R. and Scherrer, G. (2018) Endogenous and Exogenous Opioids in Pain. Annual Review of Neuroscience, 41, 453-473. [Google Scholar] [CrossRef] [PubMed]
|
|
[24]
|
Nersesyan, H. and Slavin, K.V. (2007) Current Approach to Cancer Pain Management: Availability and Implications of Different Treatment Options. Therapeutics and Clinical Risk Management, 3, 381-400.
|
|
[25]
|
Harris, D.G. (2014) Management of Pain in Advanced Disease. British Medical Bulletin, 110, 117-128. [Google Scholar] [CrossRef] [PubMed]
|
|
[26]
|
Gendron, L., Cahill, C.M., von Zastrow, M., Schiller, P.W. and Pineyro, G. (2016) Molecular Pharmacology of δ-Opioid Receptors. Pharmacological Reviews, 68, 631-700. [Google Scholar] [CrossRef] [PubMed]
|
|
[27]
|
Wolny-Rokicka, E., Sutkowski, K., Grządziel, A., Dorsz, Ż., Tukiendorf, A., Lipiński, J., et al. (2016) Tolerance and Efficacy of Palliative Radiotherapy for Advanced Pancreatic Cancer: A Retrospective Analysis of Single-Institutional Experiences. Molecular and Clinical Oncology, 4, 1088-1092. [Google Scholar] [CrossRef] [PubMed]
|
|
[28]
|
Tello Valverde, C.P., Ebrahimi, G., Sprangers, M.A., Pateras, K., Bruynzeel, A.M.E., Jacobs, M., et al. (2024) Impact of Short-Course Palliative Radiation Therapy on Pancreatic Cancer-Related Pain: Prospective Phase 2 Nonrandomized PAINPANC Trial. International Journal of Radiation Oncology Biology Physics, 118, 352-361. [Google Scholar] [CrossRef] [PubMed]
|
|
[29]
|
Wang, Y., Timotin, E., Zia, W., Farrell, T., Reiter, H., Chan, B., et al. (2018) Pain Palliation Using Hypofractionated Radiotherapy for Unresectable Pancreatic Cancer. Journal of Medical Imaging and Radiation Sciences, 49, 293-300. [Google Scholar] [CrossRef] [PubMed]
|
|
[30]
|
Buwenge, M., Macchia, G., Arcelli, A., Frakulli, R., Fuccio, L., Guerri, S., et al. (2018) Stereotactic Radiotherapy of Pancreatic Cancer: A Systematic Review on Pain Relief. Journal of Pain Research, 11, 2169-2178. [Google Scholar] [CrossRef] [PubMed]
|
|
[31]
|
Buwenge, M., Arcelli, A., Cellini, F., Deodato, F., Macchia, G., Cilla, S., et al. (2022) Pain Relief after Stereotactic Radiotherapy of Pancreatic Adenocarcinoma: An Updated Systematic Review. Current Oncology, 29, 2616-2629. [Google Scholar] [CrossRef] [PubMed]
|
|
[32]
|
Lawrence, Y.R., Miszczyk, M., Dawson, L.A., Diaz Pardo, D.A., Aguiar, A., Limon, D., et al. (2024) Celiac Plexus Radiosurgery for Pain Management in Advanced Cancer: A Multicentre, Single-Arm, Phase 2 Trial. The Lancet Oncology, 25, 1070-1079. [Google Scholar] [CrossRef] [PubMed]
|
|
[33]
|
Liu, Y., Chen, M., Liu, L., Shen, Z. and Wu, B. (2025) High-Intensity Focused Ultrasound (HIFU) in Pancreatic Cancer-Related Pain: Current Evidence and Future Directions. Ultrasound in Medicine & Biology, 51, 1639-1645. [Google Scholar] [CrossRef] [PubMed]
|
|
[34]
|
Fergadi, M.P., Magouliotis, D.E., Rountas, C., Vlychou, M., Athanasiou, T., Symeonidis, D., et al. (2021) A Meta-Analysis Evaluating the Role of High-Intensity Focused Ultrasound (HIFU) as a Fourth Treatment Modality for Patients with Locally Advanced Pancreatic Cancer. Abdominal Radiology, 47, 254-264. [Google Scholar] [CrossRef] [PubMed]
|
|
[35]
|
Yang, W., Zhu, B., Li, J., Diao, L., Ma, K. and Fan, Y. (2019) High-Intensity Focused Ultrasound Ablation for Advanced Pancreatic Cancer. Journal of Cancer Research and Therapeutics, 15, Article No. 831. [Google Scholar] [CrossRef] [PubMed]
|
|
[36]
|
Ning, Z.Y., Cheng, C.S., Xie, J., Chen, Q.W., Xu, L.T., Zhuang, L.P., et al. (2016) A Retrospective Analysis of Survival Factors of High Intensity Focused Ultrasound (HIFU) Treatment for Unresectable Pancreatic Cancer. Discovery Medicine, 21, 435-445.
|
|
[37]
|
Marinova, M., Feradova, H., Gonzalez-Carmona, M.A., Conrad, R., Tonguc, T., Thudium, M., et al. (2021) Improving Quality of Life in Pancreatic Cancer Patients Following High-Intensity Focused Ultrasound (HIFU) in Two European Centers. European Radiology, 31, 5818-5829. [Google Scholar] [CrossRef] [PubMed]
|
|
[38]
|
Wiechowska-Kozłowska, A., Boer, K., Wójcicki, M. and Milkiewicz, P. (2012) The Efficacy and Safety of Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis for Treatment of Pain in Patients with Pancreatic Cancer. Gastroenterology Research and Practice, 2012, Article ID: 503098. [Google Scholar] [CrossRef] [PubMed]
|
|
[39]
|
Reenas, J., Dixon, B., Hendrix, J.M., et al. (2025) Celiac Plexus Block. StatPearls.
|
|
[40]
|
Eisenberg, E., Carr, D.B. and Chalmers, T.C. (1995) Neurolytic Celiac Plexus Block for Treatment of Cancer Pain: A Meta-Analysis. Anesthesia & Analgesia, 80, 290-295. [Google Scholar] [CrossRef]
|
|
[41]
|
Levy, M.J., Topazian, M.D., Wiersema, M.J., Clain, J.E., Rajan, E., Wang, K.K., et al. (2008) Initial Evaluation of the Efficacy and Safety of Endoscopic Ultrasound-Guided Direct Ganglia Neurolysis and Block. The American Journal of Gastroenterology, 103, 98-103. [Google Scholar] [CrossRef] [PubMed]
|
|
[42]
|
Eye, N., Metz, T., Arneson, F. and McKean, H.A. (2025) Impact of Intrathecal Targeted Drug Delivery (ITDD) on Oral Morphine Equivalents and Pain Scores in Advanced Pancreatic Cancer Pain. Journal of Clinical Oncology, 43, 686-686. [Google Scholar] [CrossRef]
|
|
[43]
|
Carvajal, G., Dupoiron, D., Seegers, V., Lebrec, N., Boré, F., Dubois, P., et al. (2018) Intrathecal Drug Delivery Systems for Refractory Pancreatic Cancer Pain: Observational Follow-Up Study over an 11-Year Period in a Comprehensive Cancer Center. Anesthesia & Analgesia, 126, 2038-2046. [Google Scholar] [CrossRef] [PubMed]
|
|
[44]
|
Li, J., Sheng, S., Zhang, K. and Liu, T. (2016) Pain Analysis in Patients with Pancreatic Carcinoma: Irreversible Electroporation versus Cryoablation. BioMed Research International, 2016, Article ID: 2543026. [Google Scholar] [CrossRef] [PubMed]
|
|
[45]
|
Marinova, M., Wilhelm-Buchstab, T. and Strunk, H. (2019) Advanced Pancreatic Cancer: High-Intensity Focused Ultrasound (HIFU) and Other Local Ablative Therapies. RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 191, 216-227. [Google Scholar] [CrossRef] [PubMed]
|
|
[46]
|
Whitcomb, D.C., Lehman, G.A., Vasileva, G., Malecka-Panas, E., Gubergrits, N., Shen, Y., et al. (2010) Pancrelipase Delayed-Release Capsules (CREON) for Exocrine Pancreatic Insufficiency Due to Chronic Pancreatitis or Pancreatic Surgery: A Double-Blind Randomized Trial. American Journal of Gastroenterology, 105, 2276-2286. [Google Scholar] [CrossRef] [PubMed]
|
|
[47]
|
Jia, S., Wen, F., Gong, T., Li, X., Wang, H., Sun, Y., et al. (2020) A Review on the Efficacy and Safety of Iodine-125 Seed Implantation in Unresectable Pancreatic Cancers. International Journal of Radiation Biology, 96, 383-389. [Google Scholar] [CrossRef] [PubMed]
|
|
[48]
|
Masuda, T., Kuramoto, M., Shimada, S., Ikeshima, S., Yamamoto, K., Nakamura, K., et al. (2014) Splanchnicectomy for Pancreatic Cancer Pain. BioMed Research International, 2014, Article ID: 941726. [Google Scholar] [CrossRef] [PubMed]
|
|
[49]
|
Vance, C.G., Dailey, D.L., Rakel, B.A. and Sluka, K.A. (2014) Using TENS for Pain Control: The State of the Evidence. Pain Management, 4, 197-209. [Google Scholar] [CrossRef] [PubMed]
|
|
[50]
|
Zhang, R., Lao, L., Ren, K. and Berman, B.M. (2014) Mechanisms of Acupuncture-Electroacupuncture on Persistent Pain. Anesthesiology, 120, 482-503. [Google Scholar] [CrossRef] [PubMed]
|
|
[51]
|
Staats, P.S., Hekmat, H., Sauter, P. and Lillemoe, K. (2001) The Effects of Alcohol Celiac Plexus Block, Pain, and Mood on Longevity in Patients with Unresectable Pancreatic Cancer: A Double-Blind, Randomized, Placebo-Controlled Study. Pain Medicine, 2, 28-34. [Google Scholar] [CrossRef] [PubMed]
|
|
[52]
|
Hendifar, A.E., Petzel, M.Q.B., Zimmers, T.A., Denlinger, C.S., Matrisian, L.M., Picozzi, V.J., et al. (2018) Pancreas Cancer-Associated Weight Loss. The Oncologist, 24, 691-701. [Google Scholar] [CrossRef] [PubMed]
|
|
[53]
|
Samala, R.V., Lagman, R.L., Najafi, S. and Fielding, F. (2021) Frequently Asked Questions about Managing Cancer Pain: An Update. Cleveland Clinic Journal of Medicine, 88, 183-191. [Google Scholar] [CrossRef] [PubMed]
|