浅谈针刺治疗干燥综合征的研究进展及展望

Research Progress and Prospects of Acupuncture Treatment for Sjögren’s Syndrome

摘要: 干燥综合征是一种慢性自身免疫性疾病，以侵犯外分泌腺体，尤其是唾液腺和泪腺为主的慢性自身免疫性疾病，临床主要表现为口干、眼干，并可伴有系统性损害。目前现代医学以替代疗法和免疫抑制剂为主，但存在疗效有限、副作用明显等问题。针刺作为中医特色疗法，在调节机体免疫功能、促进腺体分泌方面具有独特优势，近年来其应用于干燥综合征的临床与机制研究逐步深入。本文通过系统梳理国内外相关文献，从临床疗效与作用机制两方面综述针刺治疗干燥综合征的研究进展。深入探索各种针刺治疗方案，以期形成更具个体化、疗效更优的治疗方案，为针刺的临床推广应用提供依据。

Abstract: Sjögren’s syndrome is a chronic autoimmune disease that mainly affects the exocrine glands, especially the salivary and lacrimal glands. Clinical manifestations include dry mouth and eyes, and may be accompanied by systemic damage. At present, modern medicine mainly relies on alternative therapies and immunosuppressants, but there are problems such as limited efficacy and significant side effects. Acupuncture, as a characteristic therapy of traditional Chinese medicine, has unique advantages in regulating the body’s immune function and promoting glandular secretion. In recent years, its application in the clinical and mechanistic research of Sjögren’s syndrome has gradually deepened. This article reviews the research progress of acupuncture treatment for Sjögren’s syndrome from two aspects: clinical efficacy and mechanism of action, by systematically reviewing relevant literature at home and abroad. An in-depth exploration of various acupuncture treatment plans is conducted to develop more individualized and effective therapeutic approaches, thereby providing a basis for their clinical promotion and application.