调经育麟膏联合电针治疗排卵障碍性不孕症的临床观察
Clinical Observation on Tiaojing Yulin Plaster Combined with Electroacupuncture for Treatment of Ovulatory Infertility
摘要: 目的：观察调经育麟膏联合电针治疗肾虚型排卵障碍性不孕症的临床效果。方法：选取符合纳入标准的肾虚型排卵障碍性不孕症患者60例作为研究对象，将2类患者分别随机分为观察组和对照组，每组30例。观察组予中药调经育麟膏联合用灵龟八法开穴电针治疗，对照组予来曲唑片治疗，疗程为3个月经周期。观察各组治疗前后卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E2)、睾酮(T)、泌乳素(PRL)、子宫内膜厚度、卵巢功能及妊娠情况。结果：2组患者LH水平较治疗前下降，E2水平较治疗前升高(P < 0.05)，观察组FSH水平较治疗前升高(P < 0.05)，观察组在改善LH、E2水平方面优于对照组(P < 0.05)；观察组子宫内膜厚度较治疗前增加(P < 0.05)，且优于对照组(P < 0.05)；观察组排卵率高于对照组(P < 0.05)，观察组妊娠率高于对照组(P > 0.05)。结论：对于排卵障碍性不孕症患者，调经育麟膏联合电针治疗可有效调节激素水平，增加子宫内膜厚度，改善排卵情况，促进卵巢功能恢复。
Abstract: Objective: To observe the clinical effect of tiaojing Yulin Cream combined with electroacupuncture in the treatment of kidney deficiency type of ovulation disorders infertility. Methods: 60 patients with anovulatory infertility of kidney deficiency type who met the inclusion criteria were selected as the research objects. The two types of patients were randomly divided into observation group and control group, 30 cases in each group. The observation group was treated with Tiaojingyulin ointment combined with point injection of Linggui eight methods acupointing on time electroacupuncture, and the control group was treated with letrozole tablet for 3 menstrual cycles. The Follitropin beta (FSH), Lutropin Alfa (LH), estradiol (E2), testosterone (T), prolactin (PRL), endometrial thickness, ovarian function and pregnancy were observed before and after treatment. Results: The level of LH decreased and the level of E2 increased in both groups (P < 0.05). The level of FSH increased in the observation group (P < 0.05), and the Observation Group was superior to the control group in improving the levels of LH and E2(P < 0.05); the endometrial thickness of the observation group was increased compared with that before treatment (P < 0.05), and was better than that of the control group (P < 0.05); the ovulation rate of the observation group was higher than that of the control group (P < 0.05), and the pregnancy rate of observation group was higher than that of control group (P > 0.05). Conclusion: Tiaojing Yulin plaster combined with electroacupuncture can improve the clinical efficacy, regulate hormone levels, increase endometrial thickness, improve ovulation and promote the recovery of ovarian function in patients with kidney deficiency type of anovulatory infertility.
文章引用：赵青, 甘子晴, 苏以燕. 调经育麟膏联合电针治疗排卵障碍性不孕症的临床观察[J]. 临床个性化医学, 2026, 5(1): 96-101. https://doi.org/10.12677/jcpm.2026.51015

参考文献

[1] Gao, W., Ju, Y., Gao, L., Mohammed Abdalla, H. and Salum Masoud, S. (2025) Depression, Anxiety and Associated Factors among Infertile Women in Zanzibar. Journal of Psychosomatic Obstetrics & Gynecology, 46, Article ID: 2522387. [Google Scholar] [CrossRef] [PubMed]
[2] 马堃. 中西医结合诊治肾虚血瘀型排卵障碍性不孕(不育)优势的探究[J]. 中国中药杂志, 2021, 46(11): 2623-2628.
[3] 竹晓岚. 自拟中药温肾方治疗女性排卵障碍性不孕症疗效观察[J]. 辽宁中医杂志, 2024, 51(8): 123-126.
[4] Zia, T., Liaqat, I., Shahzad, K.A., Lashari, M.H., Fouad, D., Ataya, F.S., et al. (2025) Ameliorative Effect of Fagonia indica-Coated Chitosan Nanoparticles on the Ovulatory Pattern in PCOS Rat Model. Journal of Ovarian Research, 18, Article No. 44. [Google Scholar] [CrossRef] [PubMed]
[5] Du, B., Ni, M. and Chen, P. (2025) Effects of Letrozole Combined with Clomiphene in the Treatment of Polycystic Ovary Syndrome: A Meta-Analysis. BMC Women’s Health, 25, Article No. 344. [Google Scholar] [CrossRef] [PubMed]
[6] 施冬青, 唐艳, 唐李梅, 等. 针药结合治疗抗米勒管激素相关卵泡发育障碍性不孕症疗效观察[J]. 世界中医药, 2023, 18(24): 3567-3571.
[7] 王洋, 王春霞, 李鹏超, 等. 基于本虚标实探析排卵障碍性不孕症的中医治疗思路与方法[J]. 辽宁中医杂志, 2025, 52(5): 42-44.
[8] 王亦姝, 史云, 马堃, 等. 从冲任的枢机作用论治排卵障碍性不孕[J]. 中华中医药杂志, 2023, 38(1): 230-233.
[9] 江苏省中医药发展研究中心, 江苏省中医药学会, 江苏省中西医结合学会. 中医膏方临床应用与制备工艺规范[J]. 江苏中医药, 2024, 56(11): 1-7.
[10] 杨丽, 盖明辉, 张继伟, 等. 灵龟八法穴位注射按时开穴联合子午流注针法治疗肠梗阻的临床研究[J/OL]. 辽宁中医杂志: 1-15.
https://link.cnki.net/urlid/21.1128.r.20250312.1900.038, 2025-07-23.
[11] 孙巧悦, 王贺, 李京儒, 等. 王富春教授调任固冲针法治疗不孕症的经验总结[J]. 上海针灸杂志, 2025, 44(4): 387-391.
[12] 宋秀玲, 刘璐慜, 明树人, 等. 电针针刺膀胱募穴穴组治疗女性压力性尿失禁的临床研究[J]. 上海中医药杂志, 2025, 59(3): 7-11.
[13] 唐华丽, 饶钰湘, 杜东玲, 等. 针灸治疗卵巢功能减退类疾病的选穴规律[J]. 广州中医药大学学报, 2024, 41(11): 2898-2906.
[14] You, X.M., Xu, J.B., Yang, J., et al. (2023) Clinical Efficacy of Acupuncture Combined with Chinese Herbal Medication for Recurrent Implantation Failure Infertility of Kidney Deficiency and Blood Stasis and Its Effects on Serum p38MAPK and JAK/STAT Protein Expression. Chinese Acupuncture & Moxibustion, 43, 1399-1404.
[15] 魏守红, 钟好好, 李晓燕, 等. 来曲唑的不同用药方案对多囊卵巢综合征诱发排卵的临床效果研究[J]. 河北北方学院学报(自然科学版), 2025, 41(10): 35-37.
[16] 栾素娴, 马华刚, 赵文杰, 等. 不同剂量来曲唑在诱导排卵中对子宫内膜厚度影响的研究[J]. 中国计划生育学杂志, 2014, 22(1): 48-50.
[17] 张驰, 闫颖, 张晗. 针灸治疗排卵障碍性不孕症临床研究进展[J]. 河南中医, 2025, 45(3): 479-486.
[18] 单海萍, 许小凤. 排卵障碍性不孕中医药治疗研究进展[J]. 辽宁中医药大学学报, 2021, 23(7): 139-143.