多肽类药物研发现状
The Current State of Research and Development for Peptide Drugs
DOI: 10.12677/pi.2026.151001, PDF,   
作者: 薛周元, 邱 郑*:中国药科大学生命科学与技术学院,江苏 南京
关键词: 多肽药物临床研究多功能肽Peptide Drugs Clinical Research Multifunctional Peptides
摘要: 近年来,多肽药物研究取得了显著的进展,越来越多的多肽药物被开发并应用于临床。多肽药物在肿瘤、抗菌、心血管系统疾病、糖尿病等疾病的预防、诊断和治疗中得到了广泛应用,并展现出广阔的发展前景。本文旨在简要介绍多肽药物的来源、特点以及先导多肽的发现,并着重综述在不同疾病治疗领域国内外多肽药物的研发概况。新型多肽药物如多功能肽、多肽偶联药物、多肽疫苗等的出现,极大地推动了多肽药物领域的繁荣发展。本文还讨论了多肽药物未来发展和挑战,以期为该类新药的研发提供参考。
Abstract: Peptide drugs have become a prominent area of research with numerous advancements contributing to their increased development and application in clinical practice. These drugs are now widely utilized in the prevention, diagnosis and treatment of various diseases, including cancer, bacterial infections, cardiovascular disorders, and diabetes. The trend of peptide drug has shown great promise and continues to expand. This article provides a brief introduction to the origins, characteristics and discovery of lead peptides in the research. This article also focuses on summarizing the research and development of peptide drugs in different disease treatment fields. The emergence of novel peptide drugs, such as multifunctional peptides, peptide-drug conjugates, and peptide vaccines, has greatly propelled the prosperity and development of the peptide-based therapeutics field. Additionally, the article discusses the future development prospects and challenges that peptide drugs may encounter which aims to provide valuable references involved in the exploration of new peptide drugs for researchers and developers.
文章引用:薛周元, 邱郑. 多肽类药物研发现状[J]. 药物资讯, 2026, 15(1): 1-11. https://doi.org/10.12677/pi.2026.151001

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