中西医治疗慢性心力衰竭合并抑郁及焦虑状态的研究进展

Research Progress on the Treatment of Chronic Heart Failure Complicated with Depression and Anxiety by Traditional Chinese and Western Medicine

摘要: 当前慢性心力衰竭与抑郁、焦虑共病率升高，二者互为病理条件，会增加患者死亡风险，已成为临床重点问题。西医发病机制主要与神经激素调节异常及炎症反应相关，中医则以“本虚标实”为核心病机。临床形成西医、中医药及非药物干预的协同治疗格局，中西结合协同治疗疗效可观。本文系统梳理慢性心力衰竭合并抑郁及焦虑状态的发病机制、治疗策略及研究进展，以期为临床治疗提供理论与实践参考。

Abstract: Currently, the comorbidity rate of chronic heart failure (CHF) with depression and anxiety is increasing. These conditions interact as pathological factors, elevating patient mortality risk, and have become a key clinical concern. The pathogenesis in Western medicine is primarily associated with neurohormonal dysregulation and inflammatory responses, while Traditional Chinese Medicine (TCM) identifies “deficiency-root and excess-superficiality” as the core pathogenesis. A collaborative treatment landscape integrating Western medicine, TCM therapies, and non-pharmacological interventions has been established in clinical practice, with integrated Traditional Chinese and Western medicine demonstrating considerable therapeutic efficacy. This article systematically reviews the pathogenesis, treatment strategies, and research progress regarding CHF complicated with depression and anxiety, aiming to provide theoretical and practical references for clinical management.