肺炎链球菌感染合并爆发性紫癜一例报告

A Case Report of Streptococcus pneumoniae Infection Complicated with Purpura Fulminans

摘要: 本文报告了一例老年男性患者，因肺炎链球菌(Streptococcus pneumoniae)感染致脓毒血症并发爆发性紫癜(Purpura Fulminans, PF)而死亡的病例。患者因“气促伴全身酸痛1天余，加重3小时”由急诊入院，病程急剧恶化，迅速发展为感染性休克爆发性紫癜(Purpura Fulminans, PF)及多器官功能衰竭。尽管进行了积极的抗生素治疗、重症监护支持和替代治疗，患者仍在入院后48小时内死亡。本病例旨在提高对肺炎链球菌相关暴发性紫癜这一罕见但致命性并发症的认识，强调其起病急骤、病情凶险及早期识别及干预的重要性。

Abstract: This paper reports a fatal case of an elderly male patient who died of sepsis complicated with purpura fulminans (PF) caused by Streptococcus pneumoniae infection. The patient was admitted to the Emergency Department due to “dyspnea with generalized myalgia for more than 1 day, aggravated for 3 hours”. The disease progressed rapidly, evolving into septic shock, purpura fulminans (PF), and multiple organ failure. Despite aggressive antibiotic therapy, intensive care support, and replacement therapy, the patient died within 48 hours of admission. This case aims to enhance the understanding of this rare but life-threatening complication of Streptococcus pneumoniae-related purpura fulminans, emphasizing its acute onset, critical condition, and the importance of early identification and intervention.