胰岛素抵抗的实用标志物:TyG指数在代谢性疾病中的研究现状
Practical Markers of Insulin Resistance: The Current Research Status of TyG Index in Metabolic Diseases
摘要: 胰岛素抵抗是2型糖尿病、代谢综合征、代谢相关脂肪性肝病和动脉粥样硬化性心血管疾病等多种代谢性疾病的共同病理基础。近年来,肌少症及肌少性肥胖被认为是以胰岛素抵抗为核心的传统代谢性疾病谱系的新成员。甘油三酯-葡萄糖指数作为一种基于空腹甘油三酯和血糖计算的新型标志物,因其简便、经济的优点,已成为评估胰岛素抵抗的有效替代指标。本综述系统梳理了甘油三酯葡萄糖指数在上述代谢性疾病中的研究进展。
Abstract: Insulin resistance serves as a common pathological basis for various metabolic diseases, including type 2 diabetes, metabolic syndrome, metabolic dysfunction-associated steatotic liver disease, and atherosclerotic cardiovascular disease. In recent years, sarcopenia and sarcopenic obesity have been recognized as new components of the traditional metabolic disease spectrum centered on insulin resistance. The triglyceride-glucose (TyG) index, a novel marker derived from fasting triglyceride and blood glucose levels, has emerged as an effective and economical alternative for assessing insulin resistance due to its simplicity and accessibility. This review systematically summarizes recent research advances regarding the TyG index in the context of these metabolic diseases.
文章引用:方艳, 杨刚毅. 胰岛素抵抗的实用标志物:TyG指数在代谢性疾病中的研究现状[J]. 临床医学进展, 2026, 16(1): 504-513. https://doi.org/10.12677/acm.2026.161069

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