小儿推拿治疗儿童功能性便秘的机制探析

Analysis of the Mechanism of Pediatric Tuina in Treating Functional Constipation in Children

摘要: 儿童功能性便秘(FC)是常见的儿童排便障碍，现代医学治疗存在局限。小儿推拿作为传统中医外治法，在FC治疗中展现出独特优势。本文从传统中医理论出发，结合现代医学对FC多因素发病的认识，总结了推拿单独或联合其他疗法的临床应用效果。从现代医学视角探析其可能的多靶点作用机制，包括调节肠道动力、改善肠道菌群、调节神经系统功能、干预脑–肠轴以及改善局部物理环境等，为“调理脏腑”的传统理论提供了现代科学阐释。本文旨在为小儿推拿的临床推广应用提供依据，并指出未来需深化高质量临床研究、推进操作标准化及深入探索分子机制等方向。

Abstract: Functional constipation (FC) is a common pediatric defecation disorder, and modern medical treatments have certain limitations. Pediatric Tuina, as an external therapy in traditional Chinese medicine, demonstrates unique advantages in the treatment of FC. Based on traditional Chinese medicine theory and incorporating modern medical understanding of the multifactorial pathogenesis of FC, this article summarizes the clinical efficacy of Tuina alone or in combination with other therapies. From a modern medical perspective, it explores the potential multi-target mechanisms of action, including regulating intestinal motility, improving gut microbiota, modulating nervous system function, intervening in the brain-gut axis, and enhancing the local physical environment. This provides a modern scientific interpretation for the traditional theory of “regulating zang-fu organs”. The article aims to offer a basis for the clinical promotion and application of pediatric Tuina and highlights future directions, such as conducting high-quality clinical research, advancing operational standardization, and delving into molecular mechanisms.