安神补心六味丸镇静作用的研究进展

Research Progress on the Sedative Effect of Anshen Buxin Liuwei Pills

摘要: 安神补心六味丸，又名吉如和-6，是蒙医学中治疗“赫依偏盛”的经典组方，具有镇静、安神、祛“赫依”的功效，它由牛心、木香、枫香脂、丁香、肉豆蔻、广枣等6味药组成，临床上多用于治疗心悸气短。“赫依”用于推动心脏搏动和血液循环，主导精神活动，相当于神经–内分泌系统中神经递质的作用，祛“赫依”则相当于调节神经-内分泌系统的功能，从而调节心血管功能和精神活动。现代药理学已初步证明安神补心六味丸在治疗冠心病、心绞痛、心律失常等方面的作用，也被应用于心烦、焦虑、失眠等方面，但目前关于安神补心六味丸镇静作用的研究较少，本文通过收集整理文献资料，综述安神补心六味丸镇静作用的研究进展。

Abstract: Anshen Buxin Liuwei Pills, also known as Jiruhe-6, is a classic prescription in Mongolian medicine for treating “excessive Heyi” (a core concept in Mongolian medicine). It has the effects of sedation, tranquilizing the mind, and dispelling “Heyi”, and is composed of 6 medicinal ingredients, including ox heart, Aucklandia lappa (Muxiang), liquidambar resin (Fengxiangzhi), clove, nutmeg, and Choerospondias axillaris (Guangzao). Clinically, it is mainly used for treating palpitations and shortness of breath. In Mongolian medical theory, “Heyi” is responsible for promoting heartbeats, blood circulation, and governing mental activities, which is analogous to the role of neurotransmitters in the neuroendocrine system. Dispelling “Heyi” is equivalent to regulating the function of the neuroendocrine system, thereby adjusting cardiovascular function and mental activities. Modern pharmacology has initially confirmed the role of Anshen Buxin Liuwei Pills in the treatment of coronary heart disease, angina pectoris, arrhythmia and other conditions; it is also used for addressing symptoms such as dysphoria, anxiety, and insomnia. However, there is currently relatively little research on the sedative effect of Anshen Buxin Liuwei Pills. By collecting and organizing literature, this article reviews the research progress on the sedative effect of Anshen Buxin Liuwei Pills.