基于《素问·热论》三阳理论治疗外感发热的思路与案例分析
Approach and Case Analysis of Treating Exogenous Fever Based on the Three Yang Theory in “Su Wen∙Re Lun”
DOI: 10.12677/tcm.2026.151049, PDF,    科研立项经费支持
作者: 黄 凝, 艾丽红:成都中医药大学临床医学院,四川 成都;高 蓉*:成都中医药大学附属内江市中医医院肺病科,四川 内江
关键词: 《素问·热论》外感发热柴桂退热方三阳经中医疗法“Su Wen·Re Lun” Exogenous Fever Chaigui Antipyretic Formula San Yang Jing Traditional Chinese Medicine Therapy
摘要: 外感发热是一种常见病、多发病。现代医学主要采用解热镇痛、抗感染等对症治疗,退热速度快,但存在症状反复、毒副作用、耐药等问题。《素问·热论》提出的“三阳经络受病”理论,为外感发热的辨证施治提供了重要指导。本研究基于该理论,探讨自拟柴桂退热方(柴胡、桂枝、葛根等)治疗外感发热的组方规律与临床价值。通过文献研究与理论分析,阐释“三阳同治”的治法内涵,解析该方以柴胡疏解少阳、桂枝解表散寒、葛根清泄阳明、黄芩与连翘清热透邪、炙甘草调和诸药的配伍机制。结合两则典型医案,阐明该方疗效显著,患者均在24~48小时内体温恢复正常,伴随症状明显改善,且未出现不良反应。结果表明,柴桂退热方紧扣三阳病机,临床运用安全有效,为中医药治疗外感发热提供了理论依据与实践参考。
Abstract: Exogenous fever is a common and frequently occurring disease. Modern medicine mainly adopts symptomatic treatments such as antipyretic and analgesic, anti infective, etc. The fever reduction rate is fast, but there are problems such as recurrent symptoms, toxic side effects, and drug resistance. The theory of “Three Yang Meridians Suffering from Diseases” proposed in “Su Wen·Re Lun” provides important guidance for the diagnosis and treatment of external fever. Based on this theory, this study explores the composition rules and clinical value of a self formulated Chaigui antipyretic formula (Chaihu, Guizhi, Gegen, etc.) for treating external fever. Through literature research and theoretical analysis, this paper elucidates the therapeutic connotation of the “Three Yang Tongzhi” formula, and analyzes the compatibility mechanism of the formula, which uses Chaihu to relieve Shaoyang, Guizhi to relieve exterior coldness, Gegen to clear Yangming, Huangqin and Forsythia suspensa to clear heat and eliminate evil, and roasted licorice to harmonize various medicines. Based on two typical medical cases, it is demonstrated that this formula has significant therapeutic effects. Patients’ body temperature returned to normal within 24~48 hours, accompanied by significant improvement in symptoms, and no adverse reactions occurred. The results indicate that Chaigui antipyretic formula closely follows the three yang disease mechanism, and is safe and effective in clinical application, providing theoretical basis and practical reference for the treatment of exogenous fever with traditional Chinese medicine.
文章引用:黄凝, 艾丽红, 高蓉. 基于《素问·热论》三阳理论治疗外感发热的思路与案例分析[J]. 中医学, 2026, 15(1): 352-358. https://doi.org/10.12677/tcm.2026.151049

参考文献

[1] Lanza, F.L., Chan, F.K.L. and Quigley, E.M.M. (2009) Guidelines for Prevention of NSAID-Related Ulcer Complications. American Journal of Gastroenterology, 104, 728-738. [Google Scholar] [CrossRef
[2] 田代华. 黄帝内经素问[M]. 北京: 人民卫生出版社, 2005.
[3] 林昶东, 陈剑峰. 浅谈发热促进机体免疫的机制[J]. 生命的化学, 2019, 39(1): 53-58.
[4] Liu, X., Tang, Y., Liu, R., Jin, Y., Guo, J., Zhao, J., et al. (2015) Antipyretic and Anti-Inflammatory Activities of Thais Luteostoma Extracts and Underlying Mechanisms. Chinese Journal of Natural Medicines, 13, 192-198. [Google Scholar] [CrossRef] [PubMed]
[5] Ogoina, D. (2011) Fever, Fever Patterns and Diseases Called ‘Fever’—A Review. Journal of Infection and Public Health, 4, 108-124. [Google Scholar] [CrossRef] [PubMed]
[6] 张文武. 急诊内科学[M]. 北京: 人民卫生出版社, 2023.
[7] Sostres, C., Gargallo, C.J. and Lanas, A. (2022) Nonsteroidal Anti-Inflammatory Drugs and Prostaglandins in the Kidney and Cardiovascular System. British Journal of Pharmacology, 179, 1461-1476.
[8] 张希. 中医外治法治疗小儿发热的研究[J]. 吉林中医药, 2011, 31(8): 744-746.
[9] 郭颖, 朱立毅. “退热1号”治疗外感发热风热证34例临床研究[J]. 江苏中医药, 2017, 49(12): 35-37.
[10] Chinbuah, M.A., Kager, P.A., Abbey, M., Gyapong, M., Awini, E., Nonvignon, J., et al. (2012) Impact of Community Management of Fever (Using Antimalarials with or without Antibiotics) on Childhood Mortality: A Cluster-Randomized Controlled Trial in Ghana. The American Journal of Tropical Medicine and Hygiene, 87, 11-20. [Google Scholar] [CrossRef] [PubMed]
[11] 北京中医学院. 内经选读[M]. 上海: 上海科学技术出版社, 1978.
[12] 谷万里, 史载祥, 余云旭, 等. 原发性高血压的中医证型特征[J]. 中国中西医结合杂志, 2010, 30(9): 842-845.
[13] Yang, Y., Islam, M.S., Wang, J., Li, Y. and Chen, X. (2020) Traditional Chinese Medicine in the Treatment of Patients Infected with 2019-New Coronavirus (SARS-CoV-2): A Review and Perspective. International Journal of Biological Sciences, 16, 1708-1717. [Google Scholar] [CrossRef] [PubMed]
[14] Chen, Z. and Nakamura, T. (2004) Statistical Evidence for the Usefulness of Chinese Medicine in the Treatment of Sars. Phytotherapy Research, 18, 592-594. [Google Scholar] [CrossRef] [PubMed]
[15] 赵少英, 许前磊, 许向前, 等. 论艾滋病发热[J]. 中华中医药杂志, 2015, 30(12): 4239-4241.
[16] 熊益亮, 张其成. 中医三阴三阳思维的形成[J]. 中华中医药杂志, 2015, 30(9): 3061-3063.
[17] 唐利, 余佳蓓, 李慧珊, 等. 《内经》《难经》“三阴” “三阳”的指代和含义研究[J]. 世界科学技术-中医药现代化, 2021, 23(3): 918-923.
[18] 神农本草经[M]. 尚志钧, 校. 北京: 人民卫生出版社, 1982.
[19] 肖丽霞, 周辉年, 龙勃, 等. 柴胡皂苷A的药理活性和作用机制研究现状及进展[J]. 生物医学转化, 2021, 2(4): 60-66.
[20] 李时珍. 本草纲目[M]. 刘衡如, 校. 北京: 华夏出版社, 2002.
[21] 徐锋, 王德健, 王凤, 等. 桂枝挥发油的药理作用研究进展[J]. 中华中医药杂志, 2016, 31(11): 4653-4657.
[22] 陶弘景. 名医别录[M]. 尚志钧, 校. 北京: 人民卫生出版社, 1986.
[23] 薛瑾, 王庆国. 葛根素对心血管保护作用的细胞实验研究进展[C]//中华中医药学会仲景学说分会. 全国第二十一次仲景学说学术年会论文集. 北京: 北京中医药大学, 2013: 379-381.
[24] 张明月. 葛根与粉葛解热、镇痛、抗炎药效学研究及代谢组学分析[D]: [硕士学位论文]. 南昌: 江西中医药大学, 2021.
[25] 张景岳. 本草正[M]. 北京: 中医古籍出版社, 2002.
[26] 张元素. 珍珠囊[M]. 北京: 中国中医药出版社, 2007.
[27] 汪昂. 本草备要[M]. 北京: 人民卫生出版社, 2005.